Hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome: A review of diagnosis and management

C. J. Saphier, John Repke

Research output: Contribution to journalArticle

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Hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome is a form of severe preeclampsia that threatens the gravida and her fetus. In this report, the diagnostic criteria and maternal and fetal risks of HELLP are defined. Prompt recognition and treatment in tertiary centers is emphasized, because the prognosis can be adversely affected by delayed or less than optimal diagnosis and treatment. Management guidelines are offered for treating disorder. The potential roles of corticosteroids, plasmapheresis, and expectant management are critically evaluated. Subsequent pregnancy outcome, contraception, and preventative strategies are considered.

Original languageEnglish (US)
Pages (from-to)118-133
Number of pages16
JournalSeminars in Perinatology
Issue number2
Publication statusPublished - Jan 1 1998


All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

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