TY - JOUR
T1 - Heparin-Induced Thrombocytopenia
T2 - A Review for Cardiac Anesthesiologists and Intensivists
AU - Ivascu, Natalia S.
AU - Fitzgerald, Meghann
AU - Ghadimi, Kamrouz
AU - Patel, Prakash
AU - Evans, Adam S.
AU - Goeddel, Lee A.
AU - Shaefi, Shaz
AU - Klick, John
AU - Johnson, Angela
AU - Raiten, Jesse
AU - Horak, Jiri
AU - Gutsche, Jacob
PY - 2019/2
Y1 - 2019/2
N2 - Patients undergoing cardiovascular surgery may be exposed to heparin before surgery, during cardiopulmonary bypass (CPB), or in the immediate postoperative period. For this reason, cardiovascular surgery patients are at increased risk for heparin-induced thrombocytopenia (HIT), occurring in 1 to 3% of patients. The diagnosis of HIT can be difficult, if based solely on the development of thrombocytopenia, because cardiac surgical patients have multiple reasons to be thrombocytopenic. Several clinical scoring systems have been developed to reduce unnecessary testing and better define the pretest probability of HIT, which we will review in detail with a diagnostic algorithm. In addition, we will cover the prevention and treatment HIT.
AB - Patients undergoing cardiovascular surgery may be exposed to heparin before surgery, during cardiopulmonary bypass (CPB), or in the immediate postoperative period. For this reason, cardiovascular surgery patients are at increased risk for heparin-induced thrombocytopenia (HIT), occurring in 1 to 3% of patients. The diagnosis of HIT can be difficult, if based solely on the development of thrombocytopenia, because cardiac surgical patients have multiple reasons to be thrombocytopenic. Several clinical scoring systems have been developed to reduce unnecessary testing and better define the pretest probability of HIT, which we will review in detail with a diagnostic algorithm. In addition, we will cover the prevention and treatment HIT.
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U2 - 10.1053/j.jvca.2018.10.035
DO - 10.1053/j.jvca.2018.10.035
M3 - Review article
C2 - 30502310
AN - SCOPUS:85057259765
SN - 1053-0770
VL - 33
SP - 511
EP - 520
JO - Journal of Cardiothoracic and Vascular Anesthesia
JF - Journal of Cardiothoracic and Vascular Anesthesia
IS - 2
ER -