Hepatitis C virus infection: detection and treatment.

Matthew L. Rubinstein, Mary E. Miele

Research output: Contribution to journalReview article

6 Citations (Scopus)

Abstract

Hepatitis C virus (HCV) is a blood-borne virus that infects the liver. HCV affects millions of Americans, and poses a serious public health threat with sequelae such as cirrhosis, hepatocellular carcinoma, and liver failure. This paper reviews means of transmission, characteristics of the various risk groups, and clinical presentations of both the acute and chronic stages of HCV infection. Diagnostic methods, including screening and confirmatory tests, along with relevant clinical and physiologic findings are also described. Additionally, treatment strategies, in particular combination therapy with interferon alpha-2b and ribavirin, are discussed. Contraindications, side effects, and monitoring of this therapeutic modality are considered. Finally, prospective treatments are presented.

Original languageEnglish (US)
Pages (from-to)203-208
Number of pages6
JournalClinical laboratory science : journal of the American Society for Medical Technology
Volume16
Issue number4
StatePublished - Sep 1 2003

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Virus Diseases
Viruses
Hepacivirus
interferon alfa-2b
Liver
Ribavirin
Liver Failure
Therapeutic Uses
Chronic Hepatitis C
Hepatocellular Carcinoma
Fibrosis
Public health
Public Health
Screening
Blood
Monitoring
Therapeutics

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

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Hepatitis C virus infection : detection and treatment. / Rubinstein, Matthew L.; Miele, Mary E.

In: Clinical laboratory science : journal of the American Society for Medical Technology, Vol. 16, No. 4, 01.09.2003, p. 203-208.

Research output: Contribution to journalReview article

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