Abstract
Quinazoline derivatives have received great interest because of their potential biological activity. This communication describes a facile method for the synthesis of substituted thiophenopyrimidones. 2‐Amino‐3‐earbethoxy‐4,5‐tetramethylenethiophene on heating with substituted imidoyl‐chlorides, iminoethers, iminothioethers or thioamides affords thiophenopyrimidones. By using this method a number of such compounds of varying complexity were synthesized which are otherwise not so easily accessible.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 903-906 |
| Number of pages | 4 |
| Journal | Journal of Heterocyclic Chemistry |
| Volume | 13 |
| Issue number | 4 |
| DOIs |
|
| State | Published - Jan 1 1976 |
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All Science Journal Classification (ASJC) codes
- Organic Chemistry
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Heterocyclic compounds. VI. Synthesis of poly nuclear thienopyrimidine derivatives. / Manhas, M. S.; Amin, Shantu.
In: Journal of Heterocyclic Chemistry, Vol. 13, No. 4, 01.01.1976, p. 903-906.Research output: Contribution to journal › Comment/debate
TY - JOUR
T1 - Heterocyclic compounds. VI. Synthesis of poly nuclear thienopyrimidine derivatives
AU - Manhas, M. S.
AU - Amin, Shantu
PY - 1976/1/1
Y1 - 1976/1/1
N2 - Quinazoline derivatives have received great interest because of their potential biological activity. This communication describes a facile method for the synthesis of substituted thiophenopyrimidones. 2‐Amino‐3‐earbethoxy‐4,5‐tetramethylenethiophene on heating with substituted imidoyl‐chlorides, iminoethers, iminothioethers or thioamides affords thiophenopyrimidones. By using this method a number of such compounds of varying complexity were synthesized which are otherwise not so easily accessible.
AB - Quinazoline derivatives have received great interest because of their potential biological activity. This communication describes a facile method for the synthesis of substituted thiophenopyrimidones. 2‐Amino‐3‐earbethoxy‐4,5‐tetramethylenethiophene on heating with substituted imidoyl‐chlorides, iminoethers, iminothioethers or thioamides affords thiophenopyrimidones. By using this method a number of such compounds of varying complexity were synthesized which are otherwise not so easily accessible.
UR - http://www.scopus.com/inward/record.url?scp=84980314282&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84980314282&partnerID=8YFLogxK
U2 - 10.1002/jhet.5570130444
DO - 10.1002/jhet.5570130444
M3 - Comment/debate
VL - 13
SP - 903
EP - 906
JO - Journal of Heterocyclic Chemistry
JF - Journal of Heterocyclic Chemistry
SN - 0022-152X
IS - 4
ER -