Abstract
Quinazoline derivatives have received great interest because of their potential biological activity. This communication describes a facile method for the synthesis of substituted thiophenopyrimidones. 2‐Amino‐3‐earbethoxy‐4,5‐tetramethylenethiophene on heating with substituted imidoyl‐chlorides, iminoethers, iminothioethers or thioamides affords thiophenopyrimidones. By using this method a number of such compounds of varying complexity were synthesized which are otherwise not so easily accessible.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 903-906 |
| Number of pages | 4 |
| Journal | Journal of Heterocyclic Chemistry |
| Volume | 13 |
| Issue number | 4 |
| DOIs |
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| State | Published - Jan 1 1976 |
All Science Journal Classification (ASJC) codes
- Organic Chemistry
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Manhas, M. S., & Amin, S. (1976). Heterocyclic compounds. VI. Synthesis of poly nuclear thienopyrimidine derivatives. Journal of Heterocyclic Chemistry, 13(4), 903-906. https://doi.org/10.1002/jhet.5570130444