Heterocyclic compounds. VI. Synthesis of poly nuclear thienopyrimidine derivatives

M. S. Manhas, Shantu Amin

Research output: Contribution to journalComment/debate

12 Citations (Scopus)

Abstract

Quinazoline derivatives have received great interest because of their potential biological activity. This communication describes a facile method for the synthesis of substituted thiophenopyrimidones. 2‐Amino‐3‐earbethoxy‐4,5‐tetramethylenethiophene on heating with substituted imidoyl‐chlorides, iminoethers, iminothioethers or thioamides affords thiophenopyrimidones. By using this method a number of such compounds of varying complexity were synthesized which are otherwise not so easily accessible.

Original languageEnglish (US)
Pages (from-to)903-906
Number of pages4
JournalJournal of Heterocyclic Chemistry
Volume13
Issue number4
DOIs
StatePublished - Jan 1 1976

Fingerprint

Thioamides
Quinazolines
Heterocyclic Compounds
Bioactivity
Derivatives
Heating
Communication
thienopyrimidine

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

Cite this

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abstract = "Quinazoline derivatives have received great interest because of their potential biological activity. This communication describes a facile method for the synthesis of substituted thiophenopyrimidones. 2‐Amino‐3‐earbethoxy‐4,5‐tetramethylenethiophene on heating with substituted imidoyl‐chlorides, iminoethers, iminothioethers or thioamides affords thiophenopyrimidones. By using this method a number of such compounds of varying complexity were synthesized which are otherwise not so easily accessible.",
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Heterocyclic compounds. VI. Synthesis of poly nuclear thienopyrimidine derivatives. / Manhas, M. S.; Amin, Shantu.

In: Journal of Heterocyclic Chemistry, Vol. 13, No. 4, 01.01.1976, p. 903-906.

Research output: Contribution to journalComment/debate

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AB - Quinazoline derivatives have received great interest because of their potential biological activity. This communication describes a facile method for the synthesis of substituted thiophenopyrimidones. 2‐Amino‐3‐earbethoxy‐4,5‐tetramethylenethiophene on heating with substituted imidoyl‐chlorides, iminoethers, iminothioethers or thioamides affords thiophenopyrimidones. By using this method a number of such compounds of varying complexity were synthesized which are otherwise not so easily accessible.

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