Abstract
Quinazoline derivatives have received great interest because of their potential biological activity. This communication describes a facile method for the synthesis of substituted thiophenopyrimidones. 2‐Amino‐3‐earbethoxy‐4,5‐tetramethylenethiophene on heating with substituted imidoyl‐chlorides, iminoethers, iminothioethers or thioamides affords thiophenopyrimidones. By using this method a number of such compounds of varying complexity were synthesized which are otherwise not so easily accessible.
Original language | English (US) |
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Pages (from-to) | 903-906 |
Number of pages | 4 |
Journal | Journal of Heterocyclic Chemistry |
Volume | 13 |
Issue number | 4 |
DOIs |
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State | Published - Jan 1 1976 |
All Science Journal Classification (ASJC) codes
- Organic Chemistry