Heterotopic abdominal heart transplantation: A pilot study

David J. Caparrelli, Jay G. Shake, Stephen M. Cattaneo, Brendan Y. Chang, William A. Baumgartner, John V. Conte, Patricia George

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

The increasingly severe shortage of donor hearts has prompted a liberalization of what is considered an acceptable donor heart. The use of marginally acceptable organs has increased in recent years. Although these marginal donors have proved effective, there still remains a tremendous shortage of donors to treat the large number of patients who are candidates for cardiac transplantation. Further use of marginal donors is limited by the requirement to assume immediate and full support of the circulation. New strategies are required to increase donor organ use even further. The authors developed a model of heterotopic abdominal heart transplant (HAHT) to investigate the possibility of using marginal donor hearts to expand the donor pool for cardiac transplantation. The authors' goal was to show that HAHT was technically feasible and could potentially function as auxiliary circulatory support in the setting of low cardiac output. The hemodynamic and metabolic consequences of a HAHT were investigated in a pilot study that provides proof of concept and lays the groundwork for future investigations.

Original languageEnglish (US)
Pages (from-to)145-151
Number of pages7
JournalCurrent Opinion in Cardiology
Volume17
Issue number2
DOIs
StatePublished - May 11 2002

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Heart Transplantation
Tissue Donors
Transplants
Low Cardiac Output
Hemodynamics

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Caparrelli, D. J., Shake, J. G., Cattaneo, S. M., Chang, B. Y., Baumgartner, W. A., Conte, J. V., & George, P. (2002). Heterotopic abdominal heart transplantation: A pilot study. Current Opinion in Cardiology, 17(2), 145-151. https://doi.org/10.1097/00001573-200203000-00004
Caparrelli, David J. ; Shake, Jay G. ; Cattaneo, Stephen M. ; Chang, Brendan Y. ; Baumgartner, William A. ; Conte, John V. ; George, Patricia. / Heterotopic abdominal heart transplantation : A pilot study. In: Current Opinion in Cardiology. 2002 ; Vol. 17, No. 2. pp. 145-151.
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Caparrelli, DJ, Shake, JG, Cattaneo, SM, Chang, BY, Baumgartner, WA, Conte, JV & George, P 2002, 'Heterotopic abdominal heart transplantation: A pilot study', Current Opinion in Cardiology, vol. 17, no. 2, pp. 145-151. https://doi.org/10.1097/00001573-200203000-00004

Heterotopic abdominal heart transplantation : A pilot study. / Caparrelli, David J.; Shake, Jay G.; Cattaneo, Stephen M.; Chang, Brendan Y.; Baumgartner, William A.; Conte, John V.; George, Patricia.

In: Current Opinion in Cardiology, Vol. 17, No. 2, 11.05.2002, p. 145-151.

Research output: Contribution to journalReview article

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AU - Caparrelli, David J.

AU - Shake, Jay G.

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AU - George, Patricia

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Caparrelli DJ, Shake JG, Cattaneo SM, Chang BY, Baumgartner WA, Conte JV et al. Heterotopic abdominal heart transplantation: A pilot study. Current Opinion in Cardiology. 2002 May 11;17(2):145-151. https://doi.org/10.1097/00001573-200203000-00004