HIGH FREQUENCY OF Mlsa‐REACTIVITY AMONG Ab‐RESTRICTED, H‐Y‐SPECIFIC T CELL CLONES

B. Frangoulis, J. Klein

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

A high frequency (80%) of Ab‐restricted, H‐Y‐specific T cell clones, but not of Ab‐restricted LDH‐B‐specific T cell clones, was found to be Mlsa‐reactive. This reactivity could be inhibited by class II (A and E)‐specific antibodies, and required an E‐positive stimulator cell. The proliferation was also blocked by T cell receptor‐specific and by CD4‐specific antibodies. Possible interpretations of these findings are discussed.

Original languageEnglish (US)
Pages (from-to)101-109
Number of pages9
JournalInternational Journal of Immunogenetics
Volume15
Issue number1-3
DOIs
StatePublished - Feb 1988

All Science Journal Classification (ASJC) codes

  • Immunology
  • Molecular Biology
  • Genetics
  • Genetics(clinical)

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