High Performance Fourier Transform Ion Cyclotron Resonance Mass Spectrometric Detection for Capillary Electrophoresis

Steven A. Hofstadler, Joanne C. Severs, Richard D. Smith, Frank D. Swanek, Andrew G. Ewing

Research output: Contribution to journalArticlepeer-review

Abstract

We describe the current state of the on-line combination of capillary electrophoresis (CE) electrospray ionization (ESI) Fourier transform ion cyclotron resonance (FTICR) mass spectrometry (MS), and discuss aspects of the FTICR technique relevant to its use as a detection scheme for on-line separations. Aspects including sensitivity, mass resolution, duty cycle, and tandem mass spectrometric capabilities are discussed in the context of online separations with examples from the authors' laboratory.

Original languageEnglish (US)
Pages (from-to)617-621
Number of pages5
JournalHRC Journal of High Resolution Chromatography
Volume19
Issue number11
DOIs
StatePublished - Nov 1996

All Science Journal Classification (ASJC) codes

  • Chemical Engineering(all)

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