High-power acoustic insult to cells as studied by acoustic microscopy

C. Miyasaka, R. Halter, Bernhard R. Tittmann, W. Hymer, N. Nicholas

Research output: Contribution to journalConference article

1 Citation (Scopus)

Abstract

A plurality of articles discussing combined effects of acoustic high-pressure and heat caused by acoustic vibration on biological tissues and cells has been introduced. Herein, we contribute the first article describing the use of a blunt impact caused by high-power ultrasonic pulses for insulting living human skin cells, wherein the impact does not generate heat. The pulses were generated by an apparatus comprising a liquid horn (i.e., water filled horn) including a concave transducer, an apparatus comprising a solid horn (i.e., aluminum waveguide horn) including a disc transducer, and a laser induced ultrasonic shock wave system, wherein the pressures caused by the pulses were measured by a hydrophone, and wherein temperature was monitored by thermocouples. Phenomena indicating cellular insult and injury (e.g., shrinkage or lift-off) were clearly visualized with scanning acoustic microscopy with frequency at 1.0 GHz.

Original languageEnglish (US)
Pages (from-to)1273-1276
Number of pages4
JournalProceedings of the IEEE Ultrasonics Symposium
Volume2
StatePublished - Dec 1 2001
Event2001 Ultrasonics Symposium - Atlanta, GA, United States
Duration: Oct 6 2001Oct 10 2001

Fingerprint

Transducers
Acoustics
microscopy
Hydrophones
acoustics
Ultrasonic waves
Thermocouples
cells
Shock waves
Vibrations (mechanical)
Skin
transducers
Waveguides
ultrasonics
pulses
Ultrasonics
Tissue
Aluminum
heat
Lasers

All Science Journal Classification (ASJC) codes

  • Acoustics and Ultrasonics

Cite this

Miyasaka, C., Halter, R., Tittmann, B. R., Hymer, W., & Nicholas, N. (2001). High-power acoustic insult to cells as studied by acoustic microscopy. Proceedings of the IEEE Ultrasonics Symposium, 2, 1273-1276.
Miyasaka, C. ; Halter, R. ; Tittmann, Bernhard R. ; Hymer, W. ; Nicholas, N. / High-power acoustic insult to cells as studied by acoustic microscopy. In: Proceedings of the IEEE Ultrasonics Symposium. 2001 ; Vol. 2. pp. 1273-1276.
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Miyasaka, C, Halter, R, Tittmann, BR, Hymer, W & Nicholas, N 2001, 'High-power acoustic insult to cells as studied by acoustic microscopy', Proceedings of the IEEE Ultrasonics Symposium, vol. 2, pp. 1273-1276.

High-power acoustic insult to cells as studied by acoustic microscopy. / Miyasaka, C.; Halter, R.; Tittmann, Bernhard R.; Hymer, W.; Nicholas, N.

In: Proceedings of the IEEE Ultrasonics Symposium, Vol. 2, 01.12.2001, p. 1273-1276.

Research output: Contribution to journalConference article

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Miyasaka C, Halter R, Tittmann BR, Hymer W, Nicholas N. High-power acoustic insult to cells as studied by acoustic microscopy. Proceedings of the IEEE Ultrasonics Symposium. 2001 Dec 1;2:1273-1276.