Histiocytic erythema multiforme

Anita Sebastian, Connor Patterson, Andrea Zaenglein, Michael Ioffreda, Klaus Helm

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Erythema multiforme is histologically characterized by liquefactive degeneration along the dermal-epidermal junction, necrotic keratinocytes and a lymphocytic infiltrate. We report a 10-year-old boy with recurrent erythema multiforme major of undetermined etiology with unusual histologic findings. A skin biopsy taken at day 2 of his eruption revealed histologic features otherwise characteristic of erythema multiforme, but mediated instead by a CD68-positive infiltrate, resembling cutaneous Kikuchi's disease. To the best of our knowledge this is the first reported case of 'histiocytic' erythema multiforme.

Original languageEnglish (US)
Pages (from-to)1323-1325
Number of pages3
JournalJournal of Cutaneous Pathology
Volume36
Issue number12
DOIs
StatePublished - Dec 1 2009

Fingerprint

Erythema Multiforme
Histiocytic Necrotizing Lymphadenitis
Skin
Keratinocytes
Skin Diseases
Biopsy

All Science Journal Classification (ASJC) codes

  • Dermatology
  • Pathology and Forensic Medicine
  • Histology

Cite this

Sebastian, Anita ; Patterson, Connor ; Zaenglein, Andrea ; Ioffreda, Michael ; Helm, Klaus. / Histiocytic erythema multiforme. In: Journal of Cutaneous Pathology. 2009 ; Vol. 36, No. 12. pp. 1323-1325.
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Histiocytic erythema multiforme. / Sebastian, Anita; Patterson, Connor; Zaenglein, Andrea; Ioffreda, Michael; Helm, Klaus.

In: Journal of Cutaneous Pathology, Vol. 36, No. 12, 01.12.2009, p. 1323-1325.

Research output: Contribution to journalArticle

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