Histocompatibility antigens controlled by the I region of the murine H-2 complex: II. KID Region compatibility is not required for I-region cell-mediated lymphocytotoxicity*

Jan Klein, Chin Lee Chiang, Vĕra Hauptfeld

Research output: Contribution to journalArticle

53 Scopus citations

Abstract

In the cell-mediated lymphocytotoxicity assay, A.TH effector cells sensitized to A.TL lymphocytes lyse not only A.TL but also C3H/HeJ and B10.A(4R) targets. Similarly, B10.T(6R) anti-B10.AQR effector cells lyse B10.BR and B10.BYR target cells in addition to B10.AQR cells. These findings indicate that for CML to occur across the I A region barrier, compatibility at K or D regions is not required.

Original languageEnglish (US)
Pages (from-to)450-454
Number of pages5
JournalJournal of Experimental Medicine
Volume145
Issue number2
DOIs
StatePublished - Feb 1 1977

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology

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