TY - JOUR
T1 - Histocompatibility antigens controlled by the I region of the murine H-2 complex
T2 - II. KID Region compatibility is not required for I-region cell-mediated lymphocytotoxicity*
AU - Klein, Jan
AU - Chiang, Chin Lee
AU - Hauptfeld, Vĕra
PY - 1977/2/1
Y1 - 1977/2/1
N2 - In the cell-mediated lymphocytotoxicity assay, A.TH effector cells sensitized to A.TL lymphocytes lyse not only A.TL but also C3H/HeJ and B10.A(4R) targets. Similarly, B10.T(6R) anti-B10.AQR effector cells lyse B10.BR and B10.BYR target cells in addition to B10.AQR cells. These findings indicate that for CML to occur across the I A region barrier, compatibility at K or D regions is not required.
AB - In the cell-mediated lymphocytotoxicity assay, A.TH effector cells sensitized to A.TL lymphocytes lyse not only A.TL but also C3H/HeJ and B10.A(4R) targets. Similarly, B10.T(6R) anti-B10.AQR effector cells lyse B10.BR and B10.BYR target cells in addition to B10.AQR cells. These findings indicate that for CML to occur across the I A region barrier, compatibility at K or D regions is not required.
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U2 - 10.1084/jem.145.2.450
DO - 10.1084/jem.145.2.450
M3 - Article
C2 - 833548
AN - SCOPUS:0017341805
SN - 0022-1007
VL - 145
SP - 450
EP - 454
JO - Journal of Experimental Medicine
JF - Journal of Experimental Medicine
IS - 2
ER -