Abstract
Is structure, rather than sequence, the key to the successful generation of truly novel proteins? While protein evolution by homologous recombination has become an established tool to explore confined regions in sequence space, the generation of functional hybrid proteins by homology-independent methods further expands the scope of protein engineering.
Original language | English (US) |
---|---|
Pages (from-to) | 319-324 |
Number of pages | 6 |
Journal | Current Opinion in Biotechnology |
Volume | 11 |
Issue number | 4 |
DOIs | |
State | Published - Aug 1 2000 |
All Science Journal Classification (ASJC) codes
- Biotechnology
- Bioengineering
- Biomedical Engineering