In the past decade, substantial strides have been taken toward the use of human adipose-derived stromal/stem cells (hASC) in the regeneration of bone. Since the discovery of the hASC osteogenic potential, many models have combined hASC with biodegradable scaffold materials. In general, rats and immunodeficient (nude) mice models for nonweight bearing bone formation have led the way to assess hASC osteogenic potential in vivo. The goal of this review is to present an overview of the recent literature describing hASC osteogenesis in conjuction with three-dimensional scaffolds for bone regeneration.
|Original language||English (US)|
|Number of pages||13|
|Journal||Journal of Biomedical Materials Research - Part B Applied Biomaterials|
|State||Published - Jan 1 2013|
All Science Journal Classification (ASJC) codes
- Biomedical Engineering