Human genomic association studies

A primer for the infectious diseases specialist

Alison A. Motsinger, David W. Haas, Todd Hulgan, Marylyn Deriggi Ritchie

Research output: Contribution to journalReview article

11 Citations (Scopus)

Abstract

Medical science is undergoing a genomic revolution. In coming years, insights from human genomic research will increasingly influence all aspects of infectious diseases, ranging from fundamental laboratory research and clinical care to epidemiology and global health. Infectious disease specialists unfamiliar with genomic methods and computational techniques may shy away from publications that involve human genomics analyses. In this article, we discuss selected aspects of study design and statistical analysis in this area, emphasizing important pitfalls that may compromise the validity of some studies. Our goal is to provide the infectious diseases specialist with information that will aid in the critical evaluation of publications that include human genomic analyses.

Original languageEnglish (US)
Pages (from-to)1737-1744
Number of pages8
JournalJournal of Infectious Diseases
Volume195
Issue number12
DOIs
StatePublished - Jun 15 2007

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Communicable Diseases
Publications
Information Services
Genomics
Research
Epidemiology
Global Health

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health
  • Immunology

Cite this

Motsinger, Alison A. ; Haas, David W. ; Hulgan, Todd ; Ritchie, Marylyn Deriggi. / Human genomic association studies : A primer for the infectious diseases specialist. In: Journal of Infectious Diseases. 2007 ; Vol. 195, No. 12. pp. 1737-1744.
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Human genomic association studies : A primer for the infectious diseases specialist. / Motsinger, Alison A.; Haas, David W.; Hulgan, Todd; Ritchie, Marylyn Deriggi.

In: Journal of Infectious Diseases, Vol. 195, No. 12, 15.06.2007, p. 1737-1744.

Research output: Contribution to journalReview article

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