Human herpesvirus 8 seroprevalence among Tobago women and the role of sexual lifestyle behavior

Alicia McDonald, Camille C. Ragin, Frank J. Jenkins, Joel Weissfeld, John Wilson, Victor W. Wheeler, Jaquie B. Wilson, Clareann H. Bunker, Emanuela Taioli

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Human herpesvirus 8 (HHV-8) infection is present in 22.9% of Tobago men. However, seroprevalence and modes of transmission of HHV-8 among Tobago women are not known. HHV-8 seropositivity rates in Tobago women were examined and compared rates to Tobago men of similar ages. To assess possible modes of transmission, sexual behavior among Tobago women was examined to determine its association with HHV-8 seropositivity. A cross-sectional study was conducted in 213 Tobago women, ages 18-65 years, who participated in the Tobago Cervical and Oral Cancer Screening Study. HHV-8 seropositivity was determined by a monoclonal immunofluorescence assay. Age-specific rates were compared to those previously observed in men. Logistic regression analyses were performed to determine the association between HHV-8 seropositivity and sexual behavior among the women. HHV-8 seroprevalence among Tobago women was 14.1% (95% CI, 10-19%), with no significant difference with men of similar age (P-value = 0.741). Age ≤17 years at first sexual intercourse was found to have a minimal significant association with HHV-8 seropositivity (OR = 2.51, 95% CI = 1.09-5.78) in women. HHV-8 age-specific rates were similar between genders. Sexual activity may not be a major contributor to HHV-8 infection among Tobago women.

Original languageEnglish (US)
Pages (from-to)264-270
Number of pages7
JournalJournal of Medical Virology
Volume81
Issue number2
DOIs
StatePublished - Feb 1 2009

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Trinidad and Tobago
Human Herpesvirus 8
Seroepidemiologic Studies
Sexual Behavior
Life Style
Herpesviridae Infections
Coitus
Mouth Neoplasms
Early Detection of Cancer
Uterine Cervical Neoplasms
Fluorescent Antibody Technique
Cross-Sectional Studies
Logistic Models
Regression Analysis

All Science Journal Classification (ASJC) codes

  • Virology
  • Infectious Diseases

Cite this

McDonald, A., Ragin, C. C., Jenkins, F. J., Weissfeld, J., Wilson, J., Wheeler, V. W., ... Taioli, E. (2009). Human herpesvirus 8 seroprevalence among Tobago women and the role of sexual lifestyle behavior. Journal of Medical Virology, 81(2), 264-270. https://doi.org/10.1002/jmv.21346
McDonald, Alicia ; Ragin, Camille C. ; Jenkins, Frank J. ; Weissfeld, Joel ; Wilson, John ; Wheeler, Victor W. ; Wilson, Jaquie B. ; Bunker, Clareann H. ; Taioli, Emanuela. / Human herpesvirus 8 seroprevalence among Tobago women and the role of sexual lifestyle behavior. In: Journal of Medical Virology. 2009 ; Vol. 81, No. 2. pp. 264-270.
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abstract = "Human herpesvirus 8 (HHV-8) infection is present in 22.9{\%} of Tobago men. However, seroprevalence and modes of transmission of HHV-8 among Tobago women are not known. HHV-8 seropositivity rates in Tobago women were examined and compared rates to Tobago men of similar ages. To assess possible modes of transmission, sexual behavior among Tobago women was examined to determine its association with HHV-8 seropositivity. A cross-sectional study was conducted in 213 Tobago women, ages 18-65 years, who participated in the Tobago Cervical and Oral Cancer Screening Study. HHV-8 seropositivity was determined by a monoclonal immunofluorescence assay. Age-specific rates were compared to those previously observed in men. Logistic regression analyses were performed to determine the association between HHV-8 seropositivity and sexual behavior among the women. HHV-8 seroprevalence among Tobago women was 14.1{\%} (95{\%} CI, 10-19{\%}), with no significant difference with men of similar age (P-value = 0.741). Age ≤17 years at first sexual intercourse was found to have a minimal significant association with HHV-8 seropositivity (OR = 2.51, 95{\%} CI = 1.09-5.78) in women. HHV-8 age-specific rates were similar between genders. Sexual activity may not be a major contributor to HHV-8 infection among Tobago women.",
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McDonald, A, Ragin, CC, Jenkins, FJ, Weissfeld, J, Wilson, J, Wheeler, VW, Wilson, JB, Bunker, CH & Taioli, E 2009, 'Human herpesvirus 8 seroprevalence among Tobago women and the role of sexual lifestyle behavior', Journal of Medical Virology, vol. 81, no. 2, pp. 264-270. https://doi.org/10.1002/jmv.21346

Human herpesvirus 8 seroprevalence among Tobago women and the role of sexual lifestyle behavior. / McDonald, Alicia; Ragin, Camille C.; Jenkins, Frank J.; Weissfeld, Joel; Wilson, John; Wheeler, Victor W.; Wilson, Jaquie B.; Bunker, Clareann H.; Taioli, Emanuela.

In: Journal of Medical Virology, Vol. 81, No. 2, 01.02.2009, p. 264-270.

Research output: Contribution to journalArticle

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