Hunting for genes that shape human faces: Initial successes and challenges for the future

Seth M. Weinberg, Jasmien Roosenboom, John R. Shaffer, Mark D. Shriver, Joanna Wysocka, Peter Claes

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

There is ample evidence from heritability studies, genetic syndromes and experimental animal models that facial morphology is strongly influenced by genes. In this brief review, we present an up-to-date overview of the efforts to identify genes associated with the size and shape of human facial features. We discuss recent methodological advances that have led to breakthroughs, but also the multitude of challenges facing the field. We offer perspective on possible applications of this line of research, particularly in the context of the precision genomics movement.

Original languageEnglish (US)
Pages (from-to)207-212
Number of pages6
JournalOrthodontics and Craniofacial Research
Volume22
Issue numberS1
DOIs
StatePublished - May 2019

All Science Journal Classification (ASJC) codes

  • Orthodontics
  • Surgery
  • Oral Surgery
  • Otorhinolaryngology

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