Hunting for genes that shape human faces: Initial successes and challenges for the future

Seth M. Weinberg, Jasmien Roosenboom, John R. Shaffer, Mark Shriver, Joanna Wysocka, Peter Claes

Research output: Contribution to journalArticle

Abstract

There is ample evidence from heritability studies, genetic syndromes and experimental animal models that facial morphology is strongly influenced by genes. In this brief review, we present an up-to-date overview of the efforts to identify genes associated with the size and shape of human facial features. We discuss recent methodological advances that have led to breakthroughs, but also the multitude of challenges facing the field. We offer perspective on possible applications of this line of research, particularly in the context of the precision genomics movement.

Original languageEnglish (US)
Pages (from-to)207-212
Number of pages6
JournalOrthodontics and Craniofacial Research
Volume22
Issue numberS1
DOIs
StatePublished - May 1 2019

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Genomics
Genes
Animal Models
Research

All Science Journal Classification (ASJC) codes

  • Orthodontics
  • Surgery
  • Oral Surgery
  • Otorhinolaryngology

Cite this

Weinberg, Seth M. ; Roosenboom, Jasmien ; Shaffer, John R. ; Shriver, Mark ; Wysocka, Joanna ; Claes, Peter. / Hunting for genes that shape human faces : Initial successes and challenges for the future. In: Orthodontics and Craniofacial Research. 2019 ; Vol. 22, No. S1. pp. 207-212.
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Hunting for genes that shape human faces : Initial successes and challenges for the future. / Weinberg, Seth M.; Roosenboom, Jasmien; Shaffer, John R.; Shriver, Mark; Wysocka, Joanna; Claes, Peter.

In: Orthodontics and Craniofacial Research, Vol. 22, No. S1, 01.05.2019, p. 207-212.

Research output: Contribution to journalArticle

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