Hybrid wound devices for spatiotemporally controlled release kinetics

Ibrahim T. Ozbolat, Bahattin Koc

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This research presents hybrid full thickness wound devices for improved wound healing process. Firstly, a 3D wound bed surface is extracted using imaging study. Then, a 3D lofting process from our previous work [1] is applied to discretize the device geometry into a number of healing regions based on linear wound margin healing fashion. Next, CAD models are developed and inputted into a multi-nozzle rapid prototyping system for biofabrication purposes. Hybrid devices are finally fabricated with varying concentration of biological modifiers and biomaterials to control the release kinetics spatiotemporally. The proposed methodology is implemented and an illustrative hybrid wound device is presented.

Original languageEnglish (US)
Title of host publicationBiomedical and Biotechnology Engineering; Nanoengineering for Medicine and Biology
PublisherAmerican Society of Mechanical Engineers (ASME)
Pages425-427
Number of pages3
ISBN (Print)9780791854884
DOIs
StatePublished - Jan 1 2011
EventASME 2011 International Mechanical Engineering Congress and Exposition, IMECE 2011 - Denver, CO, United States
Duration: Nov 11 2011Nov 17 2011

Publication series

NameASME 2011 International Mechanical Engineering Congress and Exposition, IMECE 2011
Volume2

Other

OtherASME 2011 International Mechanical Engineering Congress and Exposition, IMECE 2011
CountryUnited States
CityDenver, CO
Period11/11/1111/17/11

All Science Journal Classification (ASJC) codes

  • Mechanical Engineering

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  • Cite this

    Ozbolat, I. T., & Koc, B. (2011). Hybrid wound devices for spatiotemporally controlled release kinetics. In Biomedical and Biotechnology Engineering; Nanoengineering for Medicine and Biology (pp. 425-427). (ASME 2011 International Mechanical Engineering Congress and Exposition, IMECE 2011; Vol. 2). American Society of Mechanical Engineers (ASME). https://doi.org/10.1115/imece2011-62254