Hydrogen sulfide donor micelles protect cardiomyocytes from ischemic cell death

T. Takatani-Nakase, M. Katayama, C. Matsui, K. Hanaoka, A. J. Van Der Vlies, K. Takahashi, I. Nakase, U. Hasegawa

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Hydrogen sulfide, an important gaseous signaling molecule in the human body, is known to protect cardiomyocytes from ischemia, a condition characterized by insufficient oxygen supply to the cells. Here we show that a nanosized H2S donor micelle releases H2S intracellularly and prevents cardiomyocyte apoptosis in an in vitro ischemia model.

Original languageEnglish (US)
Pages (from-to)1705-1708
Number of pages4
JournalMolecular BioSystems
Volume13
Issue number9
DOIs
StatePublished - 2017

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Molecular Biology

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