Hydroxyl and amino functionalized cyclometalated Ir(III) complexes

Synthesis, characterization and cytotoxicity studies

Zhaozhen Wu, Juanjuan Mu, Qiong Wang, Xing Chen, Lasse Jensen, Changqing Yi, Mei Jin Li

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

A series of Ir(III) complexes (ɤN)2Ir(N N) (N N are 4,4′-dihydroxy-2,2′-bipyridine and 4,4′-diamino-2,2′-bipyridine, and ɤN are phenylpyridine, benzo[h]quinolone, and 2-phenylquinoline) were synthesized and characterized. Two of the complexes were structurally characterized via X-ray crystallography. The photophysical and photochemical properties of these complexes were studied. Preliminary studies of their applications on pH sensing, and cell imaging were also performed.

Original languageEnglish (US)
Pages (from-to)175-182
Number of pages8
JournalJournal of Organometallic Chemistry
Volume791
DOIs
StatePublished - Jun 12 2015

Fingerprint

X ray crystallography
X Ray Crystallography
Quinolones
Cytotoxicity
Hydroxyl Radical
crystallography
Imaging techniques
synthesis
cells
x rays
2-phenylquinoline

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry
  • Materials Chemistry

Cite this

Wu, Zhaozhen ; Mu, Juanjuan ; Wang, Qiong ; Chen, Xing ; Jensen, Lasse ; Yi, Changqing ; Li, Mei Jin. / Hydroxyl and amino functionalized cyclometalated Ir(III) complexes : Synthesis, characterization and cytotoxicity studies. In: Journal of Organometallic Chemistry. 2015 ; Vol. 791. pp. 175-182.
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abstract = "A series of Ir(III) complexes (ɤN)2Ir(N N) (N N are 4,4′-dihydroxy-2,2′-bipyridine and 4,4′-diamino-2,2′-bipyridine, and ɤN are phenylpyridine, benzo[h]quinolone, and 2-phenylquinoline) were synthesized and characterized. Two of the complexes were structurally characterized via X-ray crystallography. The photophysical and photochemical properties of these complexes were studied. Preliminary studies of their applications on pH sensing, and cell imaging were also performed.",
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Hydroxyl and amino functionalized cyclometalated Ir(III) complexes : Synthesis, characterization and cytotoxicity studies. / Wu, Zhaozhen; Mu, Juanjuan; Wang, Qiong; Chen, Xing; Jensen, Lasse; Yi, Changqing; Li, Mei Jin.

In: Journal of Organometallic Chemistry, Vol. 791, 12.06.2015, p. 175-182.

Research output: Contribution to journalArticle

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T1 - Hydroxyl and amino functionalized cyclometalated Ir(III) complexes

T2 - Synthesis, characterization and cytotoxicity studies

AU - Wu, Zhaozhen

AU - Mu, Juanjuan

AU - Wang, Qiong

AU - Chen, Xing

AU - Jensen, Lasse

AU - Yi, Changqing

AU - Li, Mei Jin

PY - 2015/6/12

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AB - A series of Ir(III) complexes (ɤN)2Ir(N N) (N N are 4,4′-dihydroxy-2,2′-bipyridine and 4,4′-diamino-2,2′-bipyridine, and ɤN are phenylpyridine, benzo[h]quinolone, and 2-phenylquinoline) were synthesized and characterized. Two of the complexes were structurally characterized via X-ray crystallography. The photophysical and photochemical properties of these complexes were studied. Preliminary studies of their applications on pH sensing, and cell imaging were also performed.

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