Hyperhomocysteinemia and deep vein thrombosis in orthotopic heart transplantation: A case report

Alex Costea, Geetha Bhat

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Homocysteine has been recognized as a risk factor for atherosclerosis and arterial and venous thrombosis. Heart transplant patients have an increased prevalence of hyperhomocysteinemia. High homocysteine levels in transplant patients may promote development of cardiac allograft vasculopathy, but there is minimal information regarding the risk of venous thrombosis. The current case report illustrates the association of increased levels of homocysteine and hypercoagulable syndrome in a 36-year-old heart transplant patient with no previous history of clotting disorder. Both elevated homocysteine levels and extensive venous thrombosis responded promptly to treatment with a folate/B 12/B6 vitamin combination andenoxaparin.

Original languageEnglish (US)
Pages (from-to)161-163
Number of pages3
JournalAmerican Journal of Hematology
Volume77
Issue number2
DOIs
StatePublished - Oct 2004

All Science Journal Classification (ASJC) codes

  • Hematology

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