Hypocholesterolemic agent compactin. an alternative diels-alder strategy for the synthesis of the hexahydronaphthalene portion

Raymond L. Funk, Craig J. Mossman, Wayne E. Zeller

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

The synthesis of the hexahydronaphthalene segment (4) of compactin (1) has been accomplished in a short sequence (8 steps from 9) featuring the intramolecular Diels-Alder cycloaddition of 7b.

Original languageEnglish (US)
Pages (from-to)1655-1658
Number of pages4
JournalTetrahedron Letters
Volume25
Issue number16
DOIs
StatePublished - 1984

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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