Hypoproteinemia and Anemia in Infants With Cystic Fibrosis: A Presenting Symptom Complex Often Misdiagnosed

Peter Lee, Dietrich W. Roloff, William F. Howatt

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Infants with cystic fibrosis occasionally may present with a symptom complex of anemia, hypoproteinemia, and edema. Case reports of seven infants between the ages of 1 to 4 months who developed these abnormalities indicate that in several instances the children's condition was misdiagnosed as milk-sensitivity or milk-allergy. Furthermore, their case histories verify that their hypoalbuminemia and anemia is nutritional and is corrected when a readily absorbed diet with a pancreatic-enzyme supplement is given. A retrospective review of feeding histories of 100 infants with cystic fibrosis, as well as these case reports, indicate that affected children who are breast-fed or fed with soy-based formulas are more likely to develop the syndrome. (JAMA 228:585-588, 1974).

Original languageEnglish (US)
Pages (from-to)585-588
Number of pages4
JournalJAMA: The Journal of the American Medical Association
Volume228
Issue number5
DOIs
StatePublished - Apr 29 1974

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Hypoproteinemia
Diagnostic Errors
Cystic Fibrosis
Anemia
Milk Hypersensitivity
Hypoalbuminemia
Edema
Milk
Breast
Diet
Enzymes

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

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abstract = "Infants with cystic fibrosis occasionally may present with a symptom complex of anemia, hypoproteinemia, and edema. Case reports of seven infants between the ages of 1 to 4 months who developed these abnormalities indicate that in several instances the children's condition was misdiagnosed as milk-sensitivity or milk-allergy. Furthermore, their case histories verify that their hypoalbuminemia and anemia is nutritional and is corrected when a readily absorbed diet with a pancreatic-enzyme supplement is given. A retrospective review of feeding histories of 100 infants with cystic fibrosis, as well as these case reports, indicate that affected children who are breast-fed or fed with soy-based formulas are more likely to develop the syndrome. (JAMA 228:585-588, 1974).",
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Hypoproteinemia and Anemia in Infants With Cystic Fibrosis : A Presenting Symptom Complex Often Misdiagnosed. / Lee, Peter; Roloff, Dietrich W.; Howatt, William F.

In: JAMA: The Journal of the American Medical Association, Vol. 228, No. 5, 29.04.1974, p. 585-588.

Research output: Contribution to journalArticle

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