Hypoxic-ischemic encephalopathy: Therapeutic approaches against microvascular injury, and role of neutrophils, PAF, and free radicals

Research output: Contribution to journalReview articlepeer-review

110 Scopus citations

Abstract

The asphyxiated newborn undergoes progressive brain damage even after resuscitation. This article reviews the microvascular events that contribute to evolving brain injury. The role of neutrophils, platelet-activating factor (PAF), and free radicals is stressed as pivotal mechanisms of injury and opportunities for therapeutic intervention.

Original languageEnglish (US)
Pages (from-to)481-517
Number of pages37
JournalClinics in Perinatology
Volume22
Issue number2
DOIs
StatePublished - 1995

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

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