Identification of 2-amino-4-hydroxy substituted pteridines by gas-liquid chromatography and mass spectrometry

Tom Lloyd, Sanford Markey, Norman Weiner

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

A method for the separation and characterization of several naturally occurring and synthetic pterins is described. As little as 1 μg of biopterin, neopterin, and other pterins may be identified after quantitative conversion to trimethylsilylated derivatives followed by separation and characterization by gas chromatography and mass spectrometry. This method, combined with preliminary purification procedures, should prove useful as a rapid means of identifying small amounts of pterins normally found in a variety of biological materials.

Original languageEnglish (US)
Pages (from-to)108-112
Number of pages5
JournalAnalytical Biochemistry
Volume42
Issue number1
DOIs
StatePublished - Jul 1971

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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