IL-17: A key player in the P. acnes inflammatory cascade?

Diane M. Thiboutot, Alison M. Layton, E. Anne Eady

Research output: Contribution to journalComment/debate

26 Scopus citations

Abstract

Recent advances in our understanding of inflammatory skin diseases now afford an opportunity to delve deeper into microbial/host interactions in acne. Agak et al. report that Propionibacterium acnes induces IL-17 expression in peripheral blood mononuclear cells and present new evidence that IL-17+ cells are found in the perifollicular infiltrate of comedones. Additional studies are needed to assess the clinical relevance of IL-17 in acne.

Original languageEnglish (US)
Pages (from-to)307-310
Number of pages4
JournalJournal of Investigative Dermatology
Volume134
Issue number2
DOIs
StatePublished - Feb 2014

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All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology
  • Dermatology
  • Cell Biology

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