The dual-particle imaging system being developed at the University of Michigan was used at the Joint Research Centre in Ispra, Italy for measurements on samples of special nuclear material. A 1,150-g mixed-oxide (MOX) fuel sample was measured with various shielding configurations to determine how the presence of lead and/or polyethylene shielding degrades the system's ability to localize a source by simultaneous neutron and photon imaging. Three two-hour measurements were taken with the source shielded by an: a) 8-mm lead sheath and 5.1-cm lead bricks, b) 8-mm lead sheath and 6.5-cm polyethylene bricks, and c) 8-mm lead sheath, 5.1-cm lead bricks, and 6.5-cm polyethylene bricks. The 8-mm lead sheath was used in all cases to reduce the measured photon count rate. A bare measurement was also made by using only the 8-mm lead sheath, but the unexpected presence of additional sources has rendered the measurement unsuitable for comparison. The resulting images show that the dual-particle imaging system is able to accurately localize the MOX canister in the presence of intervening material.