Abstract
Immunoreactive met-enkephalin was measured in the adrenal, kidney, liver, and intestine of the dog using radioimmunoassay. Adrenal tissue concentrations were 20 to 200-fold higher than the other tissues studied. In response to acute hypovolemic stress, the concentration of met-enkephalin in the adrenal vein of the dog increased 6-fold over basal peripheral arterial levels. These results suggest that the canine adrenal gland is a rich source of this opioid peptide and that the adrenal releases met-enkephalin in response to acute stress.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 515-518 |
| Number of pages | 4 |
| Journal | Proceedings of the Society for Experimental Biology and Medicine |
| Volume | 173 |
| Issue number | 4 |
| DOIs | |
| State | Published - Sep 1983 |
All Science Journal Classification (ASJC) codes
- Biochemistry, Genetics and Molecular Biology(all)
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Farrell, L. D., Harrison, T. S., & Demers, L. M. (1983). Immunoreactive Met-Enkephalin in the Canine Adrenal; Response to Acute Hypovolemic Stress. Proceedings of the Society for Experimental Biology and Medicine, 173(4), 515-518. https://doi.org/10.3181/00379727-173-41680