Abstract
Immunoreactive met-enkephalin was measured in the adrenal, kidney, liver, and intestine of the dog using radioimmunoassay. Adrenal tissue concentrations were 20 to 200-fold higher than the other tissues studied. In response to acute hypovolemic stress, the concentration of met-enkephalin in the adrenal vein of the dog increased 6-fold over basal peripheral arterial levels. These results suggest that the canine adrenal gland is a rich source of this opioid peptide and that the adrenal releases met-enkephalin in response to acute stress.
Original language | English (US) |
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Pages (from-to) | 515-518 |
Number of pages | 4 |
Journal | Proceedings of the Society for Experimental Biology and Medicine |
Volume | 173 |
Issue number | 4 |
DOIs | |
State | Published - Sep 1983 |
All Science Journal Classification (ASJC) codes
- Biochemistry, Genetics and Molecular Biology(all)