Impact of acute sleep restriction on cortisol and leptin levels in young women

Antonina Omisade, Orfeu M. Buxton, Benjamin Rusak

Research output: Contribution to journalArticlepeer-review

168 Citations (SciVal)


Sleep restriction alters hormone patterns and appetite in men, but less is known about effects on women. We assessed effects of overnight sleep restriction on cortisol and leptin levels and on appetite in young women. Participants' baseline sleep duration and eating habits were monitored for a week before the study. Salivary cortisol and leptin were sampled from fifteen healthy women (aged 18-25) during two consecutive days: first after a 10. h overnight sleep opportunity (Baseline day) and then after a night including only 3. h sleep (Post sleep-restriction day). Participants also completed appetite questionnaires on both days. Sleep restriction significantly reduced morning cortisol levels (p=0.02), elevated morning leptin levels (p=0.04), elevated afternoon/evening cortisol area under the curve values (p=0.008), and slowed the decline in cortisol concentration during the day (p=0.04). Hunger and craving scores did not differ significantly between days. A single night of restricted sleep affected cortisol rhythms and morning leptin levels in young women.

Original languageEnglish (US)
Pages (from-to)651-656
Number of pages6
JournalPhysiology and Behavior
Issue number5
StatePublished - Apr 2010

All Science Journal Classification (ASJC) codes

  • Experimental and Cognitive Psychology
  • Behavioral Neuroscience


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