Abstract
Background: Determining the relative importance of factors that predict quality of life (QoL) in people with multiple sclerosis (MS) must be addressed through multiple regression metrics, e.g. relative weights, which are designed to solve colinearity problems. Objective: We aimed to compare disease variables, Expanded Disability Status Scale (EDSS), depressive symptomatology (BDI-FS), cognitive performance and coping in predicting MS patients QoL, using relative weights. Methods: We assessed 97 patients with MS, using the Functional Assessment of MS (FAMS) as the criterion. Results: EDSS predicted global and physical QoL domains, whereas BDI-FS predicted general contentment and global QoL. Conclusion: EDSS and BDI-FS are relevant determinants of QoL in people with MS.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1468-1472 |
| Number of pages | 5 |
| Journal | Multiple Sclerosis |
| Volume | 21 |
| Issue number | 11 |
| DOIs | |
| State | Published - Jan 1 2015 |
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All Science Journal Classification (ASJC) codes
- Clinical Neurology
- Neurology
- Medicine(all)
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Impact of neurological impairment, depression, cognitive function and coping on quality of life of people with multiple sclerosis : A relative importance analysis. / Fernández-Jiménez, Eduardo; Arnett, Peter Andrew.
In: Multiple Sclerosis, Vol. 21, No. 11, 01.01.2015, p. 1468-1472.Research output: Contribution to journal › Article
TY - JOUR
T1 - Impact of neurological impairment, depression, cognitive function and coping on quality of life of people with multiple sclerosis
T2 - A relative importance analysis
AU - Fernández-Jiménez, Eduardo
AU - Arnett, Peter Andrew
PY - 2015/1/1
Y1 - 2015/1/1
N2 - Background: Determining the relative importance of factors that predict quality of life (QoL) in people with multiple sclerosis (MS) must be addressed through multiple regression metrics, e.g. relative weights, which are designed to solve colinearity problems. Objective: We aimed to compare disease variables, Expanded Disability Status Scale (EDSS), depressive symptomatology (BDI-FS), cognitive performance and coping in predicting MS patients QoL, using relative weights. Methods: We assessed 97 patients with MS, using the Functional Assessment of MS (FAMS) as the criterion. Results: EDSS predicted global and physical QoL domains, whereas BDI-FS predicted general contentment and global QoL. Conclusion: EDSS and BDI-FS are relevant determinants of QoL in people with MS.
AB - Background: Determining the relative importance of factors that predict quality of life (QoL) in people with multiple sclerosis (MS) must be addressed through multiple regression metrics, e.g. relative weights, which are designed to solve colinearity problems. Objective: We aimed to compare disease variables, Expanded Disability Status Scale (EDSS), depressive symptomatology (BDI-FS), cognitive performance and coping in predicting MS patients QoL, using relative weights. Methods: We assessed 97 patients with MS, using the Functional Assessment of MS (FAMS) as the criterion. Results: EDSS predicted global and physical QoL domains, whereas BDI-FS predicted general contentment and global QoL. Conclusion: EDSS and BDI-FS are relevant determinants of QoL in people with MS.
UR - http://www.scopus.com/inward/record.url?scp=84943170931&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84943170931&partnerID=8YFLogxK
U2 - 10.1177/1352458514562439
DO - 10.1177/1352458514562439
M3 - Article
C2 - 25533298
AN - SCOPUS:84985994163
VL - 21
SP - 1468
EP - 1472
JO - Multiple Sclerosis
JF - Multiple Sclerosis
SN - 1352-4585
IS - 11
ER -