Impact of skeletal complications on patients' quality of life, mobility, and functional independence

Luis Costa, Xavier Badia, Edward Chow, Allan Lipton, Andrew Wardley

Research output: Contribution to journalReview articlepeer-review

137 Scopus citations

Abstract

Introduction: Skeletal-related events (SREs) from malignant bone disease cause considerable morbidity and can dramatically reduce patients' quality of life. Discussion: Pathologic fractures often require surgical intervention and palliative radiotherapy. Thus, patients suffer impaired mobility, loss of functional independence, and diminished health-related quality of life (HRQOL). Bisphosphonates can delay the onset and reduce the incidence of SREs and have become the standard of care for the treatment of malignant bone disease; however, minimal information on the effects of bisphosphonate treatment on HRQOL is available. Targeted HRQOL assessments for patients with malignant bone disease are currently under development and are discussed herein.

Original languageEnglish (US)
Pages (from-to)879-889
Number of pages11
JournalSupportive Care in Cancer
Volume16
Issue number8
DOIs
StatePublished - Aug 1 2008

All Science Journal Classification (ASJC) codes

  • Oncology

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