Impact of surgery for stage IA non-smallcell lung cancer on patient quality of life

International Early Lung Cancer Action Program (I-ELCAP) investigators

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Background There is a paucity of literature comparing quality of life (QoL) before and after surgery in stage IA lung cancer, where surgical resection is the recommended curative treatment. Objective To assess the impact of surgery on physical and mental health-related QoL in patients with stage IA lung cancer treated with surgical resection. Methods Participants in the I-ELCAP cohort who were diagnosed with their frst primary pathologic stage IA non-small-cell lung cancer, underwent surgery, and provided follow-up information on QoL 1 year later were included in the present analysis (N = 107). QoL information was collected using the SF-12 (12-item Short Form Health Survey), which generates 2 component scores related to mental health and physical health. Results Statistical analyses indicated that physical health QoL was signifcantly worsened from before surgery to after surgery, whereas mental health QoL marginally improved from before to after surgery. Physical health QoL worsened for women from baseline to follow-up, but not for men. Only lobectomy (not limited resection) had an impact on QoL from before to after surgery. Limitations Results are considered preliminary given the small sample size and multiple comparisons. Conclusions The current study fndings have implications for lung cancer health care professionals in regard to how they can most effectively present the possible impact of surgery on quality of life to this subset of patients in which disease has not yet signifcantly progressed.

Original languageEnglish (US)
Pages (from-to)37-44
Number of pages8
JournalJournal of Community and Supportive Oncology
Volume14
Issue number1
DOIs
StatePublished - Jan 1 2016

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Lung Neoplasms
Quality of Life
Mental Health
Health
Health Surveys
Non-Small Cell Lung Carcinoma
Sample Size
Delivery of Health Care

All Science Journal Classification (ASJC) codes

  • Hematology
  • Oncology

Cite this

International Early Lung Cancer Action Program (I-ELCAP) investigators. / Impact of surgery for stage IA non-smallcell lung cancer on patient quality of life. In: Journal of Community and Supportive Oncology. 2016 ; Vol. 14, No. 1. pp. 37-44.
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title = "Impact of surgery for stage IA non-smallcell lung cancer on patient quality of life",
abstract = "Background There is a paucity of literature comparing quality of life (QoL) before and after surgery in stage IA lung cancer, where surgical resection is the recommended curative treatment. Objective To assess the impact of surgery on physical and mental health-related QoL in patients with stage IA lung cancer treated with surgical resection. Methods Participants in the I-ELCAP cohort who were diagnosed with their frst primary pathologic stage IA non-small-cell lung cancer, underwent surgery, and provided follow-up information on QoL 1 year later were included in the present analysis (N = 107). QoL information was collected using the SF-12 (12-item Short Form Health Survey), which generates 2 component scores related to mental health and physical health. Results Statistical analyses indicated that physical health QoL was signifcantly worsened from before surgery to after surgery, whereas mental health QoL marginally improved from before to after surgery. Physical health QoL worsened for women from baseline to follow-up, but not for men. Only lobectomy (not limited resection) had an impact on QoL from before to after surgery. Limitations Results are considered preliminary given the small sample size and multiple comparisons. Conclusions The current study fndings have implications for lung cancer health care professionals in regard to how they can most effectively present the possible impact of surgery on quality of life to this subset of patients in which disease has not yet signifcantly progressed.",
author = "{International Early Lung Cancer Action Program (I-ELCAP) investigators} and Schwartz, {Rebecca M.} and Rowena Yip and Ingram Olkin and Daniel Sikavi and Emanuela Taioli and Claudia Henschke and Yankelevitz, {David F.} and Dongming Xu and Mary Salvatore and Raja Flores and Andrea Wolf and McCauley, {Dorothy I.} and Mildred Chen and Libby, {Daniel M.} and Smith, {James P.} and Mark Pasmantier and Nasser Altorki and Reeves, {A. P.} and Steven Markowitz and Albert Miller and Deval, {Jose Cervera} and Heidi Roberts and Demetris Patsios and Shusuke Sone and Takaomi Hanaoka and Javier Zulueta and {De Torres}, Juan and Lozano, {Maria D.} and Ralph Aye and Kristin Manning and Tomas Bauer and Stefano Canitano and Salvatore Giunta and Enser Cole and Karl Klingler and Austin, {John H.M.} and Pearson, {Gregory D.N.} and Dorith Shaham and Cheryl Aylesworth and Patrick Meyers and Shahriyour Andaz and Davood Vafai and David Naidich and Georgeann McGuinness and Barry Sheppard and Matthew Rifkin and Torsen, {M. Kristin} and Richard Hansen and Samuel Kopel and Alan Litwin",
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International Early Lung Cancer Action Program (I-ELCAP) investigators 2016, 'Impact of surgery for stage IA non-smallcell lung cancer on patient quality of life', Journal of Community and Supportive Oncology, vol. 14, no. 1, pp. 37-44. https://doi.org/10.12788/jcso.0205

Impact of surgery for stage IA non-smallcell lung cancer on patient quality of life. / International Early Lung Cancer Action Program (I-ELCAP) investigators.

In: Journal of Community and Supportive Oncology, Vol. 14, No. 1, 01.01.2016, p. 37-44.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Impact of surgery for stage IA non-smallcell lung cancer on patient quality of life

AU - International Early Lung Cancer Action Program (I-ELCAP) investigators

AU - Schwartz, Rebecca M.

AU - Yip, Rowena

AU - Olkin, Ingram

AU - Sikavi, Daniel

AU - Taioli, Emanuela

AU - Henschke, Claudia

AU - Yankelevitz, David F.

AU - Xu, Dongming

AU - Salvatore, Mary

AU - Flores, Raja

AU - Wolf, Andrea

AU - McCauley, Dorothy I.

AU - Chen, Mildred

AU - Libby, Daniel M.

AU - Smith, James P.

AU - Pasmantier, Mark

AU - Altorki, Nasser

AU - Reeves, A. P.

AU - Markowitz, Steven

AU - Miller, Albert

AU - Deval, Jose Cervera

AU - Roberts, Heidi

AU - Patsios, Demetris

AU - Sone, Shusuke

AU - Hanaoka, Takaomi

AU - Zulueta, Javier

AU - De Torres, Juan

AU - Lozano, Maria D.

AU - Aye, Ralph

AU - Manning, Kristin

AU - Bauer, Tomas

AU - Canitano, Stefano

AU - Giunta, Salvatore

AU - Cole, Enser

AU - Klingler, Karl

AU - Austin, John H.M.

AU - Pearson, Gregory D.N.

AU - Shaham, Dorith

AU - Aylesworth, Cheryl

AU - Meyers, Patrick

AU - Andaz, Shahriyour

AU - Vafai, Davood

AU - Naidich, David

AU - McGuinness, Georgeann

AU - Sheppard, Barry

AU - Rifkin, Matthew

AU - Torsen, M. Kristin

AU - Hansen, Richard

AU - Kopel, Samuel

AU - Litwin, Alan

PY - 2016/1/1

Y1 - 2016/1/1

N2 - Background There is a paucity of literature comparing quality of life (QoL) before and after surgery in stage IA lung cancer, where surgical resection is the recommended curative treatment. Objective To assess the impact of surgery on physical and mental health-related QoL in patients with stage IA lung cancer treated with surgical resection. Methods Participants in the I-ELCAP cohort who were diagnosed with their frst primary pathologic stage IA non-small-cell lung cancer, underwent surgery, and provided follow-up information on QoL 1 year later were included in the present analysis (N = 107). QoL information was collected using the SF-12 (12-item Short Form Health Survey), which generates 2 component scores related to mental health and physical health. Results Statistical analyses indicated that physical health QoL was signifcantly worsened from before surgery to after surgery, whereas mental health QoL marginally improved from before to after surgery. Physical health QoL worsened for women from baseline to follow-up, but not for men. Only lobectomy (not limited resection) had an impact on QoL from before to after surgery. Limitations Results are considered preliminary given the small sample size and multiple comparisons. Conclusions The current study fndings have implications for lung cancer health care professionals in regard to how they can most effectively present the possible impact of surgery on quality of life to this subset of patients in which disease has not yet signifcantly progressed.

AB - Background There is a paucity of literature comparing quality of life (QoL) before and after surgery in stage IA lung cancer, where surgical resection is the recommended curative treatment. Objective To assess the impact of surgery on physical and mental health-related QoL in patients with stage IA lung cancer treated with surgical resection. Methods Participants in the I-ELCAP cohort who were diagnosed with their frst primary pathologic stage IA non-small-cell lung cancer, underwent surgery, and provided follow-up information on QoL 1 year later were included in the present analysis (N = 107). QoL information was collected using the SF-12 (12-item Short Form Health Survey), which generates 2 component scores related to mental health and physical health. Results Statistical analyses indicated that physical health QoL was signifcantly worsened from before surgery to after surgery, whereas mental health QoL marginally improved from before to after surgery. Physical health QoL worsened for women from baseline to follow-up, but not for men. Only lobectomy (not limited resection) had an impact on QoL from before to after surgery. Limitations Results are considered preliminary given the small sample size and multiple comparisons. Conclusions The current study fndings have implications for lung cancer health care professionals in regard to how they can most effectively present the possible impact of surgery on quality of life to this subset of patients in which disease has not yet signifcantly progressed.

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U2 - 10.12788/jcso.0205

DO - 10.12788/jcso.0205

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EP - 44

JO - Journal of Community and Supportive Oncology

JF - Journal of Community and Supportive Oncology

SN - 2330-7749

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