Improved method for purification of toxic peptides produced by cyanobacteria

Ken ichi Harada, Makoto Suzuki, Andrew M. Dahlem, Val R. Beasley, Wayne W. Carmichael, Kenneth L. Rinehart

Research output: Contribution to journalArticlepeer-review

139 Scopus citations

Abstract

K. Harada, M. Suzuki, A. M. Dahlem, V. R. Beasley, W. W. Carmichael and K. L. Rinehart, Jr. Improved method for purification of toxic peptides produced by cyanobacteria. Toxicon26, 433 - 439, 1988. - The improved method consists of ODS-silica gel extraction, and separation on silica gel and HPLC with UV (238 nm) detector. The method has been successfully applied to the isolation of toxic peptides from the Monroe and M-228 strains of Microcystis aeruginosa. This method reduces toxin extraction and separation time, and so enables a rapid isolation of peptide toxins from cyanobacteria.

Original languageEnglish (US)
Pages (from-to)433-439
Number of pages7
JournalToxicon
Volume26
Issue number5
DOIs
StatePublished - 1988

All Science Journal Classification (ASJC) codes

  • Toxicology

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