Improved quality of life in patients with generalized cardiovascular metabolic disease on a prepared diet

Daniel C. Hatton, Robert Brian Haynes, Suzanne Oparil, Penny Margaret Kris-Etherton, F. Xavier Pi-Sunyer, Lawrence M. Resnick, Judith S. Stern, Sharon Clark, Margaret McMahon, Cynthia Morris, Jill Metz, Ann Ward, Scott Holcomb, David A. McCarron

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Current dietary recommendations for cardiovascular disease risk reduction and recommended dietary allowances (RDAs) were used to develop a nutritionally complete prepackaged prepared meal plan specifically designed to reduce the risk of cardiovascular disease. In the current study we tested patient acceptance of the diet as defined by measures of quality of life. In a randomized, parallel-design, multicenter clinical trial, 77 persons with hypertension, diabetes mellitus, dyslipidemia, or a combination of two or more of these conditions were recruited and randomly assigned to either a prepared meal plan (n = 39) or a comparable self-selected diet (n = 38) for 10 wk. The prepared meal plan met both the RDAs for all essential micronutrients and the dietary recommendations of national health organizations for macronutrients, cholesterol, sodium, and fiber. The prescribed self-selected diet was matched for macronutrients. Quality of life, as measured by a battery of instruments, was the major endpoint. Individuals consuming the prepared meal plan had significant improvements in mental health (P < 0.01), general perceived health (P < 0.005), daily activities (P < 0.05), work performance (p < 0.005), affect (P < 0.01), and nutritional health perceptions (P < 0.001), and reductions in nutrition hassles based on a standardized questionnaire (P < 0.001). The self-selected diet group had significant improvements in nutritional health perceptions (P < 0.001) and affect (P < 0.001). There were significant improvements in weight (P < 0.001), blood pressure (P < 0.001), cholesterol (P < 0.002), low- density lipoproteins (P < 0.001), glucose (P < 0.014), and glycated hemoglobin (Hb A(1c)) (P < 0.004) that were comparable in both groups. In summary, this study shows that a nutritionally complete diet, whether prepackaged or self-selected, improves multiple risk factors for cardiovascular disease. The prepackaged prepared meal plan had the added benefit of a greater improvement in quality of life.

Original languageEnglish (US)
Pages (from-to)935-943
Number of pages9
JournalAmerican Journal of Clinical Nutrition
Volume64
Issue number6
DOIs
StatePublished - Jan 1 1996

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Metabolic Diseases
Meals
Cardiovascular Diseases
Quality of Life
Diet
Recommended Dietary Allowances
Health
Cholesterol
Micronutrients
Glycosylated Hemoglobin A
Risk Reduction Behavior
Dyslipidemias
LDL Lipoproteins
Multicenter Studies
Diabetes Mellitus
Mental Health
Sodium
Clinical Trials
Organizations
Blood Pressure

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Hatton, Daniel C. ; Haynes, Robert Brian ; Oparil, Suzanne ; Kris-Etherton, Penny Margaret ; Pi-Sunyer, F. Xavier ; Resnick, Lawrence M. ; Stern, Judith S. ; Clark, Sharon ; McMahon, Margaret ; Morris, Cynthia ; Metz, Jill ; Ward, Ann ; Holcomb, Scott ; McCarron, David A. / Improved quality of life in patients with generalized cardiovascular metabolic disease on a prepared diet. In: American Journal of Clinical Nutrition. 1996 ; Vol. 64, No. 6. pp. 935-943.
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Hatton, DC, Haynes, RB, Oparil, S, Kris-Etherton, PM, Pi-Sunyer, FX, Resnick, LM, Stern, JS, Clark, S, McMahon, M, Morris, C, Metz, J, Ward, A, Holcomb, S & McCarron, DA 1996, 'Improved quality of life in patients with generalized cardiovascular metabolic disease on a prepared diet', American Journal of Clinical Nutrition, vol. 64, no. 6, pp. 935-943. https://doi.org/10.1093/ajcn/64.6.935

Improved quality of life in patients with generalized cardiovascular metabolic disease on a prepared diet. / Hatton, Daniel C.; Haynes, Robert Brian; Oparil, Suzanne; Kris-Etherton, Penny Margaret; Pi-Sunyer, F. Xavier; Resnick, Lawrence M.; Stern, Judith S.; Clark, Sharon; McMahon, Margaret; Morris, Cynthia; Metz, Jill; Ward, Ann; Holcomb, Scott; McCarron, David A.

In: American Journal of Clinical Nutrition, Vol. 64, No. 6, 01.01.1996, p. 935-943.

Research output: Contribution to journalArticle

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AU - Pi-Sunyer, F. Xavier

AU - Resnick, Lawrence M.

AU - Stern, Judith S.

AU - Clark, Sharon

AU - McMahon, Margaret

AU - Morris, Cynthia

AU - Metz, Jill

AU - Ward, Ann

AU - Holcomb, Scott

AU - McCarron, David A.

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