In situ electrokinetic stringency control for multiplexed electrochemical pathogen sensing

Tingting Liu, Mandy L.Y. Sin, Pak Kin Wong

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper describes in situ electrokinetic stringency control for multiplexed detection of phylogenetically similar uropa-thogens toward point-of-care diagnostics of urinary tract infections (UTI). By directly implementing electrokinetics on the electrodes of a SAM-based electrochemical sensor, we demonstrate that in situ stringency control allows discrimination of single nucleotide mismatches and multiplexed detection of uropathogenic bacteria that have similar 16S rRNA sequences including P. mirabilis, P. aeruginosa and E. coli.

Original languageEnglish (US)
Title of host publication15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Pages1870-1872
Number of pages3
StatePublished - Dec 1 2011
Event15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 - Seattle, WA, United States
Duration: Oct 2 2011Oct 6 2011

Publication series

Name15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Volume3

Other

Other15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
CountryUnited States
CitySeattle, WA
Period10/2/1110/6/11

Fingerprint

Pathogens
Electrochemical sensors
Nucleotides
Escherichia coli
Bacteria
Electrodes

All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering

Cite this

Liu, T., Sin, M. L. Y., & Wong, P. K. (2011). In situ electrokinetic stringency control for multiplexed electrochemical pathogen sensing. In 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 (pp. 1870-1872). (15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011; Vol. 3).
Liu, Tingting ; Sin, Mandy L.Y. ; Wong, Pak Kin. / In situ electrokinetic stringency control for multiplexed electrochemical pathogen sensing. 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. 2011. pp. 1870-1872 (15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011).
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abstract = "This paper describes in situ electrokinetic stringency control for multiplexed detection of phylogenetically similar uropa-thogens toward point-of-care diagnostics of urinary tract infections (UTI). By directly implementing electrokinetics on the electrodes of a SAM-based electrochemical sensor, we demonstrate that in situ stringency control allows discrimination of single nucleotide mismatches and multiplexed detection of uropathogenic bacteria that have similar 16S rRNA sequences including P. mirabilis, P. aeruginosa and E. coli.",
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Liu, T, Sin, MLY & Wong, PK 2011, In situ electrokinetic stringency control for multiplexed electrochemical pathogen sensing. in 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011, vol. 3, pp. 1870-1872, 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011, Seattle, WA, United States, 10/2/11.

In situ electrokinetic stringency control for multiplexed electrochemical pathogen sensing. / Liu, Tingting; Sin, Mandy L.Y.; Wong, Pak Kin.

15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. 2011. p. 1870-1872 (15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011; Vol. 3).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Liu T, Sin MLY, Wong PK. In situ electrokinetic stringency control for multiplexed electrochemical pathogen sensing. In 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. 2011. p. 1870-1872. (15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011).