The in vitro activity of CI-934, a new quinolone antimicrobial, was compared with that of ciprofloxacin against selected gram-positive bacteria. Concentrations of CI-934 required to inhibit 90% of strains (MIC90) were twofold to eightfold lower than those of ciprofloxacin. With the exception of Streptococcus faecium, all isolates were inhibited by CI-934 at concentrations ≤1.0 μg/ml.
All Science Journal Classification (ASJC) codes
- Applied Microbiology and Biotechnology
- Immunology and Allergy
- Infectious Diseases