In vitro and animal models of human immunodeficiency virus infection of the central nervous system

Chadd E. Nesbit, Stanley A. Schwartz

Research output: Contribution to journalShort surveypeer-review

5 Scopus citations

Abstract

Each of the model systems outlined in this review has applicability to HIV research. Obviously, some are more useful than others, and refinement of the presently available systems is occurring continually. Further development of these models will enable the research community to broaden our knowledge of the pathogenesis of AIDS encephalopathy. However, effective treatment of this major complication of HIV infection remains elusive. The further development of nonprimate animal systems to assess the efficacy of potential therapies for AIDS encephalopathy is an important goal.

Original languageEnglish (US)
Pages (from-to)515-524
Number of pages10
JournalClinical and Diagnostic Laboratory Immunology
Volume9
Issue number3
DOIs
StatePublished - 2002

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology
  • Clinical Biochemistry
  • Microbiology (medical)

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