TY - JOUR
T1 - In vitro and animal models of human immunodeficiency virus infection of the central nervous system
AU - Nesbit, Chadd E.
AU - Schwartz, Stanley A.
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2002
Y1 - 2002
N2 - Each of the model systems outlined in this review has applicability to HIV research. Obviously, some are more useful than others, and refinement of the presently available systems is occurring continually. Further development of these models will enable the research community to broaden our knowledge of the pathogenesis of AIDS encephalopathy. However, effective treatment of this major complication of HIV infection remains elusive. The further development of nonprimate animal systems to assess the efficacy of potential therapies for AIDS encephalopathy is an important goal.
AB - Each of the model systems outlined in this review has applicability to HIV research. Obviously, some are more useful than others, and refinement of the presently available systems is occurring continually. Further development of these models will enable the research community to broaden our knowledge of the pathogenesis of AIDS encephalopathy. However, effective treatment of this major complication of HIV infection remains elusive. The further development of nonprimate animal systems to assess the efficacy of potential therapies for AIDS encephalopathy is an important goal.
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U2 - 10.1128/CDLI.9.3.515-524.2002
DO - 10.1128/CDLI.9.3.515-524.2002
M3 - Short survey
C2 - 11986254
AN - SCOPUS:0036111240
VL - 9
SP - 515
EP - 524
JO - Clinical and Diagnostic Laboratory Immunology
JF - Clinical and Diagnostic Laboratory Immunology
SN - 1071-412X
IS - 3
ER -