In vivo versus in vitro polymerization of acrylic bone cement: Effect on material properties

W. L. Bargar, S. A. Brown, H. A. Paul, T. Voegli, Y. Hseih, N. Sharkey

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Flexural strength and molecular weight of polymethylmethacrylate bone cement were determined for cement polymerized in vivo in a canine total hip replacement and cement from the same batch polymerized in vitro. Both in vivo and in vitro samples showed a slight increase in flexural strength and modulus at 2 weeks, followed by a nearly equivalent decline at 8 weeks. In vitro and in vivo samples exhibit a comparable stress to failure, but the in vivo samples show a significantly increased strain and decreased modulus. Cement from the proximal region of the prosthesis has significantly decreased flexural strength, lower modulus, and lower molecular weight than cement from the distal region and plug, suggesting that failures in the proximal region of a prosthesis may be due to inferior physical and mechanical properties of the bone cement in that region.

Original languageEnglish (US)
Pages (from-to)86-89
Number of pages4
JournalJournal of Orthopaedic Research
Volume4
Issue number1
DOIs
StatePublished - 1986

All Science Journal Classification (ASJC) codes

  • Orthopedics and Sports Medicine

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