Increased Hydrogel Swelling Induced by Absorption of Small Molecules

Changwoo Nam, Tawanda Zimudzi, Geoffrey M. Geise, Michael Anthony Hickner

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The water and small molecule uptake behavior of amphiphilic diacrylate terminated poly(dimethylsiloxane) (PDMSDA)/poly(ethylene glycol diacrylate) (PEGDA) cross-linked hydrogels were studied using attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy. These hydrogel networks absorbed more water as the PEGDA content of the network increased. In contrast to typical osmotic deswelling behavior that occurs when liquid water equilibrated hydrogels are immersed in small molecule solutions with water activities less than unity, water-swollen gels immersed in 2-acrylamido-2-methylpropanesulfonic acid (AMPS-H) solutions rapidly regained their water content within 4 min following an initial deswelling response. In situ ATR-FTIR analysis of the hydrogel film during the dynamic swelling experiment indicated that small molecule absorption into the gel played an important role in inducing gel reswelling in low water activity solutions. This aspect of polymer gel water uptake and interaction with small molecules is important for optimizing hydrogel coatings and hydrophilic polymer applications where there is an interaction between the internal chemical structure of the gel and electrolytes or other molecules in solution.

Original languageEnglish (US)
Pages (from-to)14263-14270
Number of pages8
JournalACS Applied Materials and Interfaces
Volume8
Issue number22
DOIs
StatePublished - Jun 8 2016

Fingerprint

Hydrogel
Hydrogels
Swelling
Molecules
Water
Gels
Polyethylene glycols
Polymers
Polydimethylsiloxane
Water content
Electrolytes
Fourier transform infrared spectroscopy
Fourier transforms
Infrared radiation
Coatings
Acids
Liquids

All Science Journal Classification (ASJC) codes

  • Materials Science(all)

Cite this

@article{dbe7c30cbc6f4cdfb66356af24993efe,
title = "Increased Hydrogel Swelling Induced by Absorption of Small Molecules",
abstract = "The water and small molecule uptake behavior of amphiphilic diacrylate terminated poly(dimethylsiloxane) (PDMSDA)/poly(ethylene glycol diacrylate) (PEGDA) cross-linked hydrogels were studied using attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy. These hydrogel networks absorbed more water as the PEGDA content of the network increased. In contrast to typical osmotic deswelling behavior that occurs when liquid water equilibrated hydrogels are immersed in small molecule solutions with water activities less than unity, water-swollen gels immersed in 2-acrylamido-2-methylpropanesulfonic acid (AMPS-H) solutions rapidly regained their water content within 4 min following an initial deswelling response. In situ ATR-FTIR analysis of the hydrogel film during the dynamic swelling experiment indicated that small molecule absorption into the gel played an important role in inducing gel reswelling in low water activity solutions. This aspect of polymer gel water uptake and interaction with small molecules is important for optimizing hydrogel coatings and hydrophilic polymer applications where there is an interaction between the internal chemical structure of the gel and electrolytes or other molecules in solution.",
author = "Changwoo Nam and Tawanda Zimudzi and Geise, {Geoffrey M.} and Hickner, {Michael Anthony}",
year = "2016",
month = "6",
day = "8",
doi = "10.1021/acsami.6b02069",
language = "English (US)",
volume = "8",
pages = "14263--14270",
journal = "ACS applied materials & interfaces",
issn = "1944-8244",
publisher = "American Chemical Society",
number = "22",

}

Increased Hydrogel Swelling Induced by Absorption of Small Molecules. / Nam, Changwoo; Zimudzi, Tawanda; Geise, Geoffrey M.; Hickner, Michael Anthony.

In: ACS Applied Materials and Interfaces, Vol. 8, No. 22, 08.06.2016, p. 14263-14270.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Increased Hydrogel Swelling Induced by Absorption of Small Molecules

AU - Nam, Changwoo

AU - Zimudzi, Tawanda

AU - Geise, Geoffrey M.

AU - Hickner, Michael Anthony

PY - 2016/6/8

Y1 - 2016/6/8

N2 - The water and small molecule uptake behavior of amphiphilic diacrylate terminated poly(dimethylsiloxane) (PDMSDA)/poly(ethylene glycol diacrylate) (PEGDA) cross-linked hydrogels were studied using attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy. These hydrogel networks absorbed more water as the PEGDA content of the network increased. In contrast to typical osmotic deswelling behavior that occurs when liquid water equilibrated hydrogels are immersed in small molecule solutions with water activities less than unity, water-swollen gels immersed in 2-acrylamido-2-methylpropanesulfonic acid (AMPS-H) solutions rapidly regained their water content within 4 min following an initial deswelling response. In situ ATR-FTIR analysis of the hydrogel film during the dynamic swelling experiment indicated that small molecule absorption into the gel played an important role in inducing gel reswelling in low water activity solutions. This aspect of polymer gel water uptake and interaction with small molecules is important for optimizing hydrogel coatings and hydrophilic polymer applications where there is an interaction between the internal chemical structure of the gel and electrolytes or other molecules in solution.

AB - The water and small molecule uptake behavior of amphiphilic diacrylate terminated poly(dimethylsiloxane) (PDMSDA)/poly(ethylene glycol diacrylate) (PEGDA) cross-linked hydrogels were studied using attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy. These hydrogel networks absorbed more water as the PEGDA content of the network increased. In contrast to typical osmotic deswelling behavior that occurs when liquid water equilibrated hydrogels are immersed in small molecule solutions with water activities less than unity, water-swollen gels immersed in 2-acrylamido-2-methylpropanesulfonic acid (AMPS-H) solutions rapidly regained their water content within 4 min following an initial deswelling response. In situ ATR-FTIR analysis of the hydrogel film during the dynamic swelling experiment indicated that small molecule absorption into the gel played an important role in inducing gel reswelling in low water activity solutions. This aspect of polymer gel water uptake and interaction with small molecules is important for optimizing hydrogel coatings and hydrophilic polymer applications where there is an interaction between the internal chemical structure of the gel and electrolytes or other molecules in solution.

UR - http://www.scopus.com/inward/record.url?scp=84974852039&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84974852039&partnerID=8YFLogxK

U2 - 10.1021/acsami.6b02069

DO - 10.1021/acsami.6b02069

M3 - Article

C2 - 27159118

AN - SCOPUS:84974852039

VL - 8

SP - 14263

EP - 14270

JO - ACS applied materials & interfaces

JF - ACS applied materials & interfaces

SN - 1944-8244

IS - 22

ER -