Indications and applications of arterial stents for stroke prevention in atherosclerotic intracranial stenosis

Jeremy D. Fields, Kenneth C. Liu, Stanley L. Barnwell, Wayne M. Clark, Helmi L. Lutsep

Research output: Contribution to journalReview article

6 Citations (Scopus)

Abstract

Intracranial stenosis accounts for 8-10% of all ischemic strokes in North America, a frequency slightly less than that of extracranial carotid stenosis. Among patients presenting with transient ischemic attack or stroke due to intracranial stenosis, the risk of recurrent stroke in the first year after initial symptoms is about 14%. Those with high-risk features (recent stroke and severe stenosis) have up to a 23% rate of recurrent stroke in the year after their initial event. Angioplasty with stenting has emerged as a potential treatment strategy, particularly in high-risk patients, although evidence is currently limited to uncontrolled prospective trials and retrospective case series. In this article, we critically review the clinical results supporting the use of stenting and highlight some key considerations in the application of this technology, including patient selection, procedural management, technical issues, and risk factors for complications and in-stent restenosis.

Original languageEnglish (US)
Pages (from-to)20-28
Number of pages9
JournalCurrent Cardiology Reports
Volume12
Issue number1
DOIs
StatePublished - Jan 1 2010

Fingerprint

Stents
Pathologic Constriction
Stroke
Carotid Stenosis
Transient Ischemic Attack
North America
Angioplasty
Patient Selection
Technology
Therapeutics

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Fields, Jeremy D. ; Liu, Kenneth C. ; Barnwell, Stanley L. ; Clark, Wayne M. ; Lutsep, Helmi L. / Indications and applications of arterial stents for stroke prevention in atherosclerotic intracranial stenosis. In: Current Cardiology Reports. 2010 ; Vol. 12, No. 1. pp. 20-28.
@article{7116c11eaa984ec385b229d90aead09f,
title = "Indications and applications of arterial stents for stroke prevention in atherosclerotic intracranial stenosis",
abstract = "Intracranial stenosis accounts for 8-10{\%} of all ischemic strokes in North America, a frequency slightly less than that of extracranial carotid stenosis. Among patients presenting with transient ischemic attack or stroke due to intracranial stenosis, the risk of recurrent stroke in the first year after initial symptoms is about 14{\%}. Those with high-risk features (recent stroke and severe stenosis) have up to a 23{\%} rate of recurrent stroke in the year after their initial event. Angioplasty with stenting has emerged as a potential treatment strategy, particularly in high-risk patients, although evidence is currently limited to uncontrolled prospective trials and retrospective case series. In this article, we critically review the clinical results supporting the use of stenting and highlight some key considerations in the application of this technology, including patient selection, procedural management, technical issues, and risk factors for complications and in-stent restenosis.",
author = "Fields, {Jeremy D.} and Liu, {Kenneth C.} and Barnwell, {Stanley L.} and Clark, {Wayne M.} and Lutsep, {Helmi L.}",
year = "2010",
month = "1",
day = "1",
doi = "10.1007/s11886-009-0070-4",
language = "English (US)",
volume = "12",
pages = "20--28",
journal = "Current Cardiology Reports",
issn = "1523-3782",
publisher = "Current Medicine Group",
number = "1",

}

Indications and applications of arterial stents for stroke prevention in atherosclerotic intracranial stenosis. / Fields, Jeremy D.; Liu, Kenneth C.; Barnwell, Stanley L.; Clark, Wayne M.; Lutsep, Helmi L.

In: Current Cardiology Reports, Vol. 12, No. 1, 01.01.2010, p. 20-28.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Indications and applications of arterial stents for stroke prevention in atherosclerotic intracranial stenosis

AU - Fields, Jeremy D.

AU - Liu, Kenneth C.

AU - Barnwell, Stanley L.

AU - Clark, Wayne M.

AU - Lutsep, Helmi L.

PY - 2010/1/1

Y1 - 2010/1/1

N2 - Intracranial stenosis accounts for 8-10% of all ischemic strokes in North America, a frequency slightly less than that of extracranial carotid stenosis. Among patients presenting with transient ischemic attack or stroke due to intracranial stenosis, the risk of recurrent stroke in the first year after initial symptoms is about 14%. Those with high-risk features (recent stroke and severe stenosis) have up to a 23% rate of recurrent stroke in the year after their initial event. Angioplasty with stenting has emerged as a potential treatment strategy, particularly in high-risk patients, although evidence is currently limited to uncontrolled prospective trials and retrospective case series. In this article, we critically review the clinical results supporting the use of stenting and highlight some key considerations in the application of this technology, including patient selection, procedural management, technical issues, and risk factors for complications and in-stent restenosis.

AB - Intracranial stenosis accounts for 8-10% of all ischemic strokes in North America, a frequency slightly less than that of extracranial carotid stenosis. Among patients presenting with transient ischemic attack or stroke due to intracranial stenosis, the risk of recurrent stroke in the first year after initial symptoms is about 14%. Those with high-risk features (recent stroke and severe stenosis) have up to a 23% rate of recurrent stroke in the year after their initial event. Angioplasty with stenting has emerged as a potential treatment strategy, particularly in high-risk patients, although evidence is currently limited to uncontrolled prospective trials and retrospective case series. In this article, we critically review the clinical results supporting the use of stenting and highlight some key considerations in the application of this technology, including patient selection, procedural management, technical issues, and risk factors for complications and in-stent restenosis.

UR - http://www.scopus.com/inward/record.url?scp=77249168608&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77249168608&partnerID=8YFLogxK

U2 - 10.1007/s11886-009-0070-4

DO - 10.1007/s11886-009-0070-4

M3 - Review article

C2 - 20425180

AN - SCOPUS:77249168608

VL - 12

SP - 20

EP - 28

JO - Current Cardiology Reports

JF - Current Cardiology Reports

SN - 1523-3782

IS - 1

ER -