Individual and joint prevalence of three nonmotor symptoms of PD in the US general population

Honglei Chen, Xuemei Huang, Xuguang Guo, Shyamal Peddada

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Background: Some nonmotor symptoms may precede the clinical diagnosis of Parkinson's disease (PD) by years. Methods: We examined the individual and joint prevalence of depression, daytime sleepiness, and infrequent bowel movement among 10,477 participants of the US National Health and Nutrition Examination Surveys 2005-2008. Results: For all symptoms, the prevalence was higher in women than in men. Importantly, few participants had two or more symptoms: 1.3% at ages 20 to 29, 1.0% at 30 to 39, 1.2% at 40 to 49, 3.5% at 50 to 59, 1.7% at 60 to 69, 1.1% at 70 to 79, and 1.2% at ages 80 years or older in men; the corresponding prevalence in women was 3.1%, 5.2%, 5.7%, 4.1%, 3.1%, 2.3%, and 1.2%, respectively. In both men and women, depression was correlated with infrequent bowel movement and daytime sleepiness, but the latter two were mutually independent. Conclusion: The presence of multiple nonmotor symptoms was uncommon in the general population and the prevalence was higher in women than in men.

Original languageEnglish (US)
Pages (from-to)1316-1319
Number of pages4
JournalMovement Disorders
Volume29
Issue number10
DOIs
StatePublished - Jan 1 2014

Fingerprint

Parkinson Disease
Joints
Population
Nutrition Surveys

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology

Cite this

Chen, Honglei ; Huang, Xuemei ; Guo, Xuguang ; Peddada, Shyamal. / Individual and joint prevalence of three nonmotor symptoms of PD in the US general population. In: Movement Disorders. 2014 ; Vol. 29, No. 10. pp. 1316-1319.
@article{39ca14aa715d47289c8f8bcf48d7f1f0,
title = "Individual and joint prevalence of three nonmotor symptoms of PD in the US general population",
abstract = "Background: Some nonmotor symptoms may precede the clinical diagnosis of Parkinson's disease (PD) by years. Methods: We examined the individual and joint prevalence of depression, daytime sleepiness, and infrequent bowel movement among 10,477 participants of the US National Health and Nutrition Examination Surveys 2005-2008. Results: For all symptoms, the prevalence was higher in women than in men. Importantly, few participants had two or more symptoms: 1.3{\%} at ages 20 to 29, 1.0{\%} at 30 to 39, 1.2{\%} at 40 to 49, 3.5{\%} at 50 to 59, 1.7{\%} at 60 to 69, 1.1{\%} at 70 to 79, and 1.2{\%} at ages 80 years or older in men; the corresponding prevalence in women was 3.1{\%}, 5.2{\%}, 5.7{\%}, 4.1{\%}, 3.1{\%}, 2.3{\%}, and 1.2{\%}, respectively. In both men and women, depression was correlated with infrequent bowel movement and daytime sleepiness, but the latter two were mutually independent. Conclusion: The presence of multiple nonmotor symptoms was uncommon in the general population and the prevalence was higher in women than in men.",
author = "Honglei Chen and Xuemei Huang and Xuguang Guo and Shyamal Peddada",
year = "2014",
month = "1",
day = "1",
doi = "10.1002/mds.25950",
language = "English (US)",
volume = "29",
pages = "1316--1319",
journal = "Movement Disorders",
issn = "0885-3185",
publisher = "John Wiley and Sons Inc.",
number = "10",

}

Individual and joint prevalence of three nonmotor symptoms of PD in the US general population. / Chen, Honglei; Huang, Xuemei; Guo, Xuguang; Peddada, Shyamal.

In: Movement Disorders, Vol. 29, No. 10, 01.01.2014, p. 1316-1319.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Individual and joint prevalence of three nonmotor symptoms of PD in the US general population

AU - Chen, Honglei

AU - Huang, Xuemei

AU - Guo, Xuguang

AU - Peddada, Shyamal

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Background: Some nonmotor symptoms may precede the clinical diagnosis of Parkinson's disease (PD) by years. Methods: We examined the individual and joint prevalence of depression, daytime sleepiness, and infrequent bowel movement among 10,477 participants of the US National Health and Nutrition Examination Surveys 2005-2008. Results: For all symptoms, the prevalence was higher in women than in men. Importantly, few participants had two or more symptoms: 1.3% at ages 20 to 29, 1.0% at 30 to 39, 1.2% at 40 to 49, 3.5% at 50 to 59, 1.7% at 60 to 69, 1.1% at 70 to 79, and 1.2% at ages 80 years or older in men; the corresponding prevalence in women was 3.1%, 5.2%, 5.7%, 4.1%, 3.1%, 2.3%, and 1.2%, respectively. In both men and women, depression was correlated with infrequent bowel movement and daytime sleepiness, but the latter two were mutually independent. Conclusion: The presence of multiple nonmotor symptoms was uncommon in the general population and the prevalence was higher in women than in men.

AB - Background: Some nonmotor symptoms may precede the clinical diagnosis of Parkinson's disease (PD) by years. Methods: We examined the individual and joint prevalence of depression, daytime sleepiness, and infrequent bowel movement among 10,477 participants of the US National Health and Nutrition Examination Surveys 2005-2008. Results: For all symptoms, the prevalence was higher in women than in men. Importantly, few participants had two or more symptoms: 1.3% at ages 20 to 29, 1.0% at 30 to 39, 1.2% at 40 to 49, 3.5% at 50 to 59, 1.7% at 60 to 69, 1.1% at 70 to 79, and 1.2% at ages 80 years or older in men; the corresponding prevalence in women was 3.1%, 5.2%, 5.7%, 4.1%, 3.1%, 2.3%, and 1.2%, respectively. In both men and women, depression was correlated with infrequent bowel movement and daytime sleepiness, but the latter two were mutually independent. Conclusion: The presence of multiple nonmotor symptoms was uncommon in the general population and the prevalence was higher in women than in men.

UR - http://www.scopus.com/inward/record.url?scp=84908375959&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84908375959&partnerID=8YFLogxK

U2 - 10.1002/mds.25950

DO - 10.1002/mds.25950

M3 - Article

C2 - 24985078

AN - SCOPUS:84908375959

VL - 29

SP - 1316

EP - 1319

JO - Movement Disorders

JF - Movement Disorders

SN - 0885-3185

IS - 10

ER -