Indol-2-one intermediates: Mechanistic evidence and synthetic utility. Total syntheses of (±)-flustramines A and C

James R. Fuchs, Raymond L. Funk

Research output: Contribution to journalArticlepeer-review

109 Scopus citations

Abstract

(Chemical Equation Presented) A variety of 3,3-disubstituted 2-indolinones have been prepared by treatment of 3-bromo-3-alkyl-2-indolinones with dienophiles/nucleophiles in the presence of cesium carbonate. Application of this general strategy has facilitated the total syntheses of the reverse prenylated marine natural products (±)-flustramine A and (±)-flustramine C.

Original languageEnglish (US)
Pages (from-to)677-680
Number of pages4
JournalOrganic Letters
Volume7
Issue number4
DOIs
StatePublished - Feb 17 2005

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Indol-2-one intermediates: Mechanistic evidence and synthetic utility. Total syntheses of (±)-flustramines A and C'. Together they form a unique fingerprint.

Cite this