Induction of labor compared to expectant management in low-risk women and associated perinatal outcomes

Yvonne W. Cheng, Anjali J. Kaimal, Jonathan M. Snowden, James Nicholson, Aaron B. Caughey

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

Objective: We sought to examine the association of labor induction and perinatal outcomes. Study Design: This was a retrospective cohort study of low-risk nulliparous women with term, live births. Women who had induction at a given gestational age (eg, 39 weeks) were compared to delivery at a later gestation (eg, 40, 41, or 42 weeks). Results: Compared to delivery at a later gestational age, those induced at 39 weeks had a lower risk of cesarean (adjusted odds ratio [aOR], 0.90; 95% confidence interval [CI], 0.88-0.91) and labor dystocia (aOR, 0.88; 95% CI, 0.84-0.94). Their neonates had lowered risk of having 5-minute Apgar <7 (aOR, 0.81; 95% CI, 0.72-0.92), meconium aspiration syndrome (aOR, 0.30; 95% CI, 0.19-0.48), and admission to neonatal intensive care unit (aOR, 0.87; 95% CI, 0.78-0.97). Similar findings were seen for women who were induced at 40 weeks compared to delivery later. Conclusion: Induction of labor in low-risk women at term is not associated with increased risk of cesarean delivery compared to delivery later.

Original languageEnglish (US)
Pages (from-to)502.e1-502.e8
JournalAmerican Journal of Obstetrics and Gynecology
Volume207
Issue number6
DOIs
StatePublished - Jan 1 2012

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Induced Labor
Odds Ratio
Confidence Intervals
Gestational Age
Meconium Aspiration Syndrome
Term Birth
Dystocia
Neonatal Intensive Care Units
Live Birth
Cohort Studies
Retrospective Studies
Newborn Infant
Pregnancy

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynecology

Cite this

Cheng, Yvonne W. ; Kaimal, Anjali J. ; Snowden, Jonathan M. ; Nicholson, James ; Caughey, Aaron B. / Induction of labor compared to expectant management in low-risk women and associated perinatal outcomes. In: American Journal of Obstetrics and Gynecology. 2012 ; Vol. 207, No. 6. pp. 502.e1-502.e8.
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Induction of labor compared to expectant management in low-risk women and associated perinatal outcomes. / Cheng, Yvonne W.; Kaimal, Anjali J.; Snowden, Jonathan M.; Nicholson, James; Caughey, Aaron B.

In: American Journal of Obstetrics and Gynecology, Vol. 207, No. 6, 01.01.2012, p. 502.e1-502.e8.

Research output: Contribution to journalArticle

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