Inflammasome activation by propionibacterium acnes: The story of il-1 in acne continues to unfold

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15 Scopus citations

Abstract

Insights into the immune mechanisms at play in skin diseases including acne continue to be made. In this issue, Kistowska et al. confirm that Propionibacterium acnes activates inflammasomes leading to the production of IL-1β and they further identify putative mechanisms by which this process occurs. These data raise interesting questions regarding a multipronged approach by which P. acnes elicits inflammation in early versus late acne and putative differences in the effects of IL-1α and IL-1β in this disease process.

Original languageEnglish (US)
Pages (from-to)595-597
Number of pages3
JournalJournal of Investigative Dermatology
Volume134
Issue number3
DOIs
StatePublished - Mar 2014

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology
  • Dermatology
  • Cell Biology

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