Abstract
Bio-degradable Poly (l-lactic acid) (PLLA) scaffolds were prepared by using thermal liquid-liquid phase separation method. A solution of PLLA-Dioxane was prepared by dissolving PLLA in dehydrated 1, 4-Dioxane. This PLLA-Dioxane solution was then directionally frozen in vials of similar dimensions but made of different materials (borosilicate glass, aluminum and copper). The frozen solution was then placed in a freeze-dryer to allow for the frozen dioxane to sublimate or lyophilized. The porosities of the resulting PLLA scaffolds were calculated and their porous structures were studied and compared between the three different vials (and the corresponding cooling rates).
| Original language | English (US) |
|---|---|
| Title of host publication | ASME 2012 Summer Bioengineering Conference, SBC 2012 |
| Pages | 617-618 |
| Number of pages | 2 |
| DOIs | |
| State | Published - Dec 1 2012 |
| Event | ASME 2012 Summer Bioengineering Conference, SBC 2012 - Fajardo, Puerto Rico Duration: Jun 20 2012 → Jun 23 2012 |
Publication series
| Name | ASME 2012 Summer Bioengineering Conference, SBC 2012 |
|---|
Other
| Other | ASME 2012 Summer Bioengineering Conference, SBC 2012 |
|---|---|
| Country | Puerto Rico |
| City | Fajardo |
| Period | 6/20/12 → 6/23/12 |
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All Science Journal Classification (ASJC) codes
- Bioengineering
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Influence of freezing (THERMAL) profiles on the morphology and mechanical properties of poly (l-lactic acid) scaffolds. / Chinnasami, Harish; Breeden, Frank; Hayes, Daniel; Devireddy, Ram.
ASME 2012 Summer Bioengineering Conference, SBC 2012. 2012. p. 617-618 (ASME 2012 Summer Bioengineering Conference, SBC 2012).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
TY - GEN
T1 - Influence of freezing (THERMAL) profiles on the morphology and mechanical properties of poly (l-lactic acid) scaffolds
AU - Chinnasami, Harish
AU - Breeden, Frank
AU - Hayes, Daniel
AU - Devireddy, Ram
PY - 2012/12/1
Y1 - 2012/12/1
N2 - Bio-degradable Poly (l-lactic acid) (PLLA) scaffolds were prepared by using thermal liquid-liquid phase separation method. A solution of PLLA-Dioxane was prepared by dissolving PLLA in dehydrated 1, 4-Dioxane. This PLLA-Dioxane solution was then directionally frozen in vials of similar dimensions but made of different materials (borosilicate glass, aluminum and copper). The frozen solution was then placed in a freeze-dryer to allow for the frozen dioxane to sublimate or lyophilized. The porosities of the resulting PLLA scaffolds were calculated and their porous structures were studied and compared between the three different vials (and the corresponding cooling rates).
AB - Bio-degradable Poly (l-lactic acid) (PLLA) scaffolds were prepared by using thermal liquid-liquid phase separation method. A solution of PLLA-Dioxane was prepared by dissolving PLLA in dehydrated 1, 4-Dioxane. This PLLA-Dioxane solution was then directionally frozen in vials of similar dimensions but made of different materials (borosilicate glass, aluminum and copper). The frozen solution was then placed in a freeze-dryer to allow for the frozen dioxane to sublimate or lyophilized. The porosities of the resulting PLLA scaffolds were calculated and their porous structures were studied and compared between the three different vials (and the corresponding cooling rates).
UR - http://www.scopus.com/inward/record.url?scp=84882661080&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84882661080&partnerID=8YFLogxK
U2 - 10.1115/SBC2012-80119
DO - 10.1115/SBC2012-80119
M3 - Conference contribution
AN - SCOPUS:84882661080
SN - 9780791844809
T3 - ASME 2012 Summer Bioengineering Conference, SBC 2012
SP - 617
EP - 618
BT - ASME 2012 Summer Bioengineering Conference, SBC 2012
ER -