Influenza

Catharine Paules, Kanta Subbarao

Research output: Contribution to journalReview article

183 Scopus citations

Abstract

Influenza is an acute respiratory illness, caused by influenza A, B, and C viruses, that occurs in local outbreaks or seasonal epidemics. Clinical illness follows a short incubation period and presentation ranges from asymptomatic to fulminant, depending on the characteristics of both the virus and the individual host. Influenza A viruses can also cause sporadic infections or spread worldwide in a pandemic when novel strains emerge in the human population from an animal host. New approaches to influenza prevention and treatment for management of both seasonal influenza epidemics and pandemics are desirable. In this Seminar, we discuss the clinical presentation, transmission, diagnosis, management, and prevention of seasonal influenza infection. We also review the animal–human interface of influenza, with a focus on current pandemic threats.

Original languageEnglish (US)
Pages (from-to)697-708
Number of pages12
JournalThe Lancet
Volume390
Issue number10095
DOIs
StatePublished - Aug 12 2017

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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    Paules, C., & Subbarao, K. (2017). Influenza. The Lancet, 390(10095), 697-708. https://doi.org/10.1016/S0140-6736(17)30129-0