Initial experience with a self-expanding retrievable stent for recanalization of large vessel occlusions in acute ischemic stroke

Bijoy K. Menon, Puneet Kochar, Andrew Ah-Seng, Mohammed A. Almekhlafi, Jayesh Modi, John H. Wong, Mark E. Hudon, Will Morrish, Andrew M. Demchuk, Mayank Goyal

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

Introduction Quicker recanalization results in better clinical outcomes in patients with acute ischemic strokes. We describe our experience with the use of a self-expanding, fully retrievable stent in acute intracranial occlusions. Methods Patients who underwent intra-arterial procedures with a self-expanding, fully retrievable stent for acute ischemic strokes at our center in 2009 were included in this study. The primary outcome was recanalization [Thrombolysis in Myocardial Infarction (TIMI) grade 2/3] at end of procedure. Secondary endpoints were procedural interval times, incidence of vasospasm, rupture of vessels, devicerelated complications, groin complications, postprocedural intracerebral hemorrhage (ICH) on noncontrast CT, and all-cause mortality. Results Fourteen patients (mean age 62.1 years, range 34- 81 years; six males) were included in the study. Sites of occlusion are as follows: M1 middle cerebral artery (MCA, n=8), M2 MCA (n=1), proximal basilar artery (n=1), and distal basilar artery (n=4). An additional device or technique was used in 9 of 14 patients prior to the use of the retrievable stent. Twelve out of 14 (85.7%) achieved TIMI 2-3 recanalization with 4 of 14 (28.6%) achieving TIMI 3. Eight of 14 (57.1%) patients had modified Rankin Scale (0-2) at 3 months or discharge. ICH on follow-up CT was noted in 28.6% (4 of 14) of patients. All-cause mortality was 2 of 14 (14.3%). Conclusion Use of a novel self-expanding, fully retrievable stent resulted in fast and very high recanalization rates in acute ischemic strokes with intravascular occlusions.

Original languageEnglish (US)
Pages (from-to)147-154
Number of pages8
JournalNeuroradiology
Volume54
Issue number2
DOIs
StatePublished - Feb 2012

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine

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