Initiation of plant disease resistance by physical interaction of AvrPto and Pto kinase

Xiaoyan Tang; Reid D. Frederick; Jianmin Zhou; Dennis A. Halterman; Yulin Jia; Gregory B. Martin

doi:10.1126/science.274.5295.2060

Initiation of plant disease resistance by physical interaction of AvrPto and Pto kinase

Xiaoyan Tang, Reid D. Frederick, Jianmin Zhou, Dennis A. Halterman, Yulin Jia, Gregory B. Martin

Plant Pathology and Environmental Microbiology

Research output: Contribution to journal › Article › peer-review

509 Scopus citations

Abstract

Resistance to bacterial speck disease in tomato occurs when the Pto kinase in the plant responds to expression of the avirulence gene avrPto in the Pseudomonas pathogen. Transient expression of an avrPto transgene in plant cells containing Pto elicited a defense response. In the yeast two- hybrid system, the Pto kinase physically interacted with AvrPto. Alterations of AvrPto or Pto that disrupted the interaction in yeast also abolished disease resistance in plants. The physical interaction of AvrPto and Pto provides an explanation of gene-for-gene specificity in bacterial speck disease resistance.

Original language	English (US)
Pages (from-to)	2060-2063
Number of pages	4
Journal	Science
Volume	274
Issue number	5295
DOIs	https://doi.org/10.1126/science.274.5295.2060
State	Published - Dec 20 1996

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title = "Initiation of plant disease resistance by physical interaction of AvrPto and Pto kinase",

abstract = "Resistance to bacterial speck disease in tomato occurs when the Pto kinase in the plant responds to expression of the avirulence gene avrPto in the Pseudomonas pathogen. Transient expression of an avrPto transgene in plant cells containing Pto elicited a defense response. In the yeast two- hybrid system, the Pto kinase physically interacted with AvrPto. Alterations of AvrPto or Pto that disrupted the interaction in yeast also abolished disease resistance in plants. The physical interaction of AvrPto and Pto provides an explanation of gene-for-gene specificity in bacterial speck disease resistance.",

author = "Xiaoyan Tang and Frederick, {Reid D.} and Jianmin Zhou and Halterman, {Dennis A.} and Yulin Jia and Martin, {Gregory B.}",

year = "1996",

month = dec,

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doi = "10.1126/science.274.5295.2060",

language = "English (US)",

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TY - JOUR

T1 - Initiation of plant disease resistance by physical interaction of AvrPto and Pto kinase

AU - Tang, Xiaoyan

AU - Frederick, Reid D.

AU - Zhou, Jianmin

AU - Halterman, Dennis A.

AU - Jia, Yulin

AU - Martin, Gregory B.

PY - 1996/12/20

Y1 - 1996/12/20

N2 - Resistance to bacterial speck disease in tomato occurs when the Pto kinase in the plant responds to expression of the avirulence gene avrPto in the Pseudomonas pathogen. Transient expression of an avrPto transgene in plant cells containing Pto elicited a defense response. In the yeast two- hybrid system, the Pto kinase physically interacted with AvrPto. Alterations of AvrPto or Pto that disrupted the interaction in yeast also abolished disease resistance in plants. The physical interaction of AvrPto and Pto provides an explanation of gene-for-gene specificity in bacterial speck disease resistance.

AB - Resistance to bacterial speck disease in tomato occurs when the Pto kinase in the plant responds to expression of the avirulence gene avrPto in the Pseudomonas pathogen. Transient expression of an avrPto transgene in plant cells containing Pto elicited a defense response. In the yeast two- hybrid system, the Pto kinase physically interacted with AvrPto. Alterations of AvrPto or Pto that disrupted the interaction in yeast also abolished disease resistance in plants. The physical interaction of AvrPto and Pto provides an explanation of gene-for-gene specificity in bacterial speck disease resistance.

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EP - 2063

JO - Science

JF - Science

IS - 5295

ER -

Initiation of plant disease resistance by physical interaction of AvrPto and Pto kinase

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