Input optimal control strategy for the desynchronization of coupled neurons

Xile Wei, Nan Chen, Meili Lu, Bin Deng, Jiang Wang, Yanqiu Che, Chunxiao Han

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We consider the problem of desynchronizing the neurons cluster with a single optimal input. This is done through the method of discrete dynamic programming. Based on the basis of the models, such as Hodgkin-Huxley neuron model, we add the optimal control input and then study the optimal input stimulation with different coupling strengths between neurons. By appropriate discretization we can combine continuous neuron equation with discrete dynamic programming and obtain the optimal input. Also we find out that the desynchronous rates of the nervous systems are closely related to its dynamic characteristics and coupling manners.

Original languageEnglish (US)
Title of host publication2012 5th International Conference on Biomedical Engineering and Informatics, BMEI 2012
Pages1020-1024
Number of pages5
DOIs
StatePublished - Dec 1 2012
Event2012 5th International Conference on Biomedical Engineering and Informatics, BMEI 2012 - Chongqing, China
Duration: Oct 16 2012Oct 18 2012

Publication series

Name2012 5th International Conference on Biomedical Engineering and Informatics, BMEI 2012

Other

Other2012 5th International Conference on Biomedical Engineering and Informatics, BMEI 2012
CountryChina
CityChongqing
Period10/16/1210/18/12

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Health Informatics

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