Integration of biological systems with electronic-mechanical assemblies

Ning Yi, Haitao Cui, Lijie Grace Zhang, Huanyu Cheng

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Biological systems continuously interact with the surrounding environment because they are dynamically evolving. The interaction is achieved through mechanical, electrical, chemical, biological, thermal, optical, or a synergistic combination of these cues. To provide a fundamental understanding of the interaction, recent efforts that integrate biological systems with the electronic-mechanical assemblies create unique opportunities for simultaneous monitoring and eliciting the responses to the biological system. Recent innovations in materials, fabrication processes, and device integration approaches have created the enablers to yield bio-integrated devices to interface with the biological system, ranging from cells and tissues to organs and living individual. In this short review, we will provide a brief overview of the recent development on the integration of the biological systems with electronic-mechanical assemblies across multiple scales, with applications ranging from healthcare monitoring to therapeutic options such as drug delivery and rehabilitation therapies. Statement of Significance: An overview of the recent progress on the integration of the biological system with both electronic and mechanical assemblies is discussed. The integration creates the unique opportunity to simultaneously monitor and elicit the responses to the biological system, which provides a fundamental understanding of the interaction between the biological system and the electronic-mechanical assemblies. Recent innovations in materials, fabrication processes, and device integration approaches have created the enablers to yield bio-integrated devices to interface with the biological system, ranging from cells and tissues to organs and living individual.

Original languageEnglish (US)
Pages (from-to)91-111
Number of pages21
JournalActa Biomaterialia
Volume95
DOIs
StatePublished - Sep 1 2019

Fingerprint

Systems Integration
Biological systems
Equipment and Supplies
Cues
Rehabilitation
Hot Temperature
Innovation
Delivery of Health Care
Tissue
Fabrication
Therapeutics
Monitoring
Pharmaceutical Preparations
Drug delivery
Patient rehabilitation

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Biomaterials
  • Biochemistry
  • Biomedical Engineering
  • Molecular Biology

Cite this

Yi, Ning ; Cui, Haitao ; Zhang, Lijie Grace ; Cheng, Huanyu. / Integration of biological systems with electronic-mechanical assemblies. In: Acta Biomaterialia. 2019 ; Vol. 95. pp. 91-111.
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Integration of biological systems with electronic-mechanical assemblies. / Yi, Ning; Cui, Haitao; Zhang, Lijie Grace; Cheng, Huanyu.

In: Acta Biomaterialia, Vol. 95, 01.09.2019, p. 91-111.

Research output: Contribution to journalReview article

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