Intelligent, self-powered, drug delivery systems

Debabrata Patra, Samudra Sengupta, Wentao Duan, Hua Zhang, Ryan Pavlick, Ayusman Sen

Research output: Contribution to journalArticle

219 Scopus citations

Abstract

Self-propelled nano/micromotors and pumps are considered to be next generation drug delivery systems since the carriers can either propel themselves ("motor"-based drug delivery) or be delivered ("pump"-based drug delivery) to the target in response to specific biomarkers. Recently, there has been significant advancement towards developing nano/microtransporters into proof-of-concept tools for biomedical applications. This review encompasses the progress made to date on the design of synthetic nano/micromotors and pumps with respect to transportation and delivery of cargo at specific locations. Looking ahead, it is possible to imagine a day when intelligent machines navigate through the human body and perform challenging tasks.

Original languageEnglish (US)
Pages (from-to)1273-1283
Number of pages11
JournalNanoscale
Volume5
Issue number4
DOIs
StatePublished - Feb 21 2013

All Science Journal Classification (ASJC) codes

  • Materials Science(all)

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    Patra, D., Sengupta, S., Duan, W., Zhang, H., Pavlick, R., & Sen, A. (2013). Intelligent, self-powered, drug delivery systems. Nanoscale, 5(4), 1273-1283. https://doi.org/10.1039/c2nr32600k