Interaction of decay-accelerating factor with echovirus 7

Pavel Plevka, Susan Hafenstein, Katherine G. Harris, Javier O. Cifuente, Ying Zhang, Valorie D. Bowman, Paul R. Chipman, Carol M. Bator, Feng Lin, M. Edward Medof, Michael G. Rossmann

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Echovirus 7 (EV7) belongs to the Enterovirus genus within the family Picornaviridae. Many picornaviruses use IgG-like receptors that bind in the viral canyon and are required to initiate viral uncoating during infection. However, in addition, some of the enteroviruses use an alternative or additional receptor that binds outside the canyon. Decay-accelerating factor (DAF) has been identified as a cellular receptor for EV7. The crystal structure of EV7 has been determined to 3.1-Å resolution and used to interpret the 7.2-Å-resolution cryo-electron microscopy reconstruction of EV7 complexed with DAF. Each DAF binding site on EV7 is near a 2-fold icosahedral symmetry axis, which differs from the binding site of DAF on the surface of coxsackievirus B3, indicating that there are independent evolutionary processes by which DAF was selected as a picornavirus accessory receptor. This suggests that there is an advantage for these viruses to recognize DAF during the initial process of infection.

Original languageEnglish (US)
Pages (from-to)12665-12674
Number of pages10
JournalJournal of virology
Volume84
Issue number24
DOIs
StatePublished - Dec 1 2010

Fingerprint

CD55 Antigens
Human Enterovirus B
deterioration
Picornaviridae
Enterovirus
receptors
canyons
binding sites
Virus Uncoating
Binding Sites
Cryoelectron Microscopy
IgG Receptors
crystal structure
Infection
infection
Viruses
viruses

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

Cite this

Plevka, P., Hafenstein, S., Harris, K. G., Cifuente, J. O., Zhang, Y., Bowman, V. D., ... Rossmann, M. G. (2010). Interaction of decay-accelerating factor with echovirus 7. Journal of virology, 84(24), 12665-12674. https://doi.org/10.1128/JVI.00837-10
Plevka, Pavel ; Hafenstein, Susan ; Harris, Katherine G. ; Cifuente, Javier O. ; Zhang, Ying ; Bowman, Valorie D. ; Chipman, Paul R. ; Bator, Carol M. ; Lin, Feng ; Medof, M. Edward ; Rossmann, Michael G. / Interaction of decay-accelerating factor with echovirus 7. In: Journal of virology. 2010 ; Vol. 84, No. 24. pp. 12665-12674.
@article{3122100f331e41edbc924d781abda981,
title = "Interaction of decay-accelerating factor with echovirus 7",
abstract = "Echovirus 7 (EV7) belongs to the Enterovirus genus within the family Picornaviridae. Many picornaviruses use IgG-like receptors that bind in the viral canyon and are required to initiate viral uncoating during infection. However, in addition, some of the enteroviruses use an alternative or additional receptor that binds outside the canyon. Decay-accelerating factor (DAF) has been identified as a cellular receptor for EV7. The crystal structure of EV7 has been determined to 3.1-{\AA} resolution and used to interpret the 7.2-{\AA}-resolution cryo-electron microscopy reconstruction of EV7 complexed with DAF. Each DAF binding site on EV7 is near a 2-fold icosahedral symmetry axis, which differs from the binding site of DAF on the surface of coxsackievirus B3, indicating that there are independent evolutionary processes by which DAF was selected as a picornavirus accessory receptor. This suggests that there is an advantage for these viruses to recognize DAF during the initial process of infection.",
author = "Pavel Plevka and Susan Hafenstein and Harris, {Katherine G.} and Cifuente, {Javier O.} and Ying Zhang and Bowman, {Valorie D.} and Chipman, {Paul R.} and Bator, {Carol M.} and Feng Lin and Medof, {M. Edward} and Rossmann, {Michael G.}",
year = "2010",
month = "12",
day = "1",
doi = "10.1128/JVI.00837-10",
language = "English (US)",
volume = "84",
pages = "12665--12674",
journal = "Journal of Virology",
issn = "0022-538X",
publisher = "American Society for Microbiology",
number = "24",

}

Plevka, P, Hafenstein, S, Harris, KG, Cifuente, JO, Zhang, Y, Bowman, VD, Chipman, PR, Bator, CM, Lin, F, Medof, ME & Rossmann, MG 2010, 'Interaction of decay-accelerating factor with echovirus 7', Journal of virology, vol. 84, no. 24, pp. 12665-12674. https://doi.org/10.1128/JVI.00837-10

Interaction of decay-accelerating factor with echovirus 7. / Plevka, Pavel; Hafenstein, Susan; Harris, Katherine G.; Cifuente, Javier O.; Zhang, Ying; Bowman, Valorie D.; Chipman, Paul R.; Bator, Carol M.; Lin, Feng; Medof, M. Edward; Rossmann, Michael G.

In: Journal of virology, Vol. 84, No. 24, 01.12.2010, p. 12665-12674.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Interaction of decay-accelerating factor with echovirus 7

AU - Plevka, Pavel

AU - Hafenstein, Susan

AU - Harris, Katherine G.

AU - Cifuente, Javier O.

AU - Zhang, Ying

AU - Bowman, Valorie D.

AU - Chipman, Paul R.

AU - Bator, Carol M.

AU - Lin, Feng

AU - Medof, M. Edward

AU - Rossmann, Michael G.

PY - 2010/12/1

Y1 - 2010/12/1

N2 - Echovirus 7 (EV7) belongs to the Enterovirus genus within the family Picornaviridae. Many picornaviruses use IgG-like receptors that bind in the viral canyon and are required to initiate viral uncoating during infection. However, in addition, some of the enteroviruses use an alternative or additional receptor that binds outside the canyon. Decay-accelerating factor (DAF) has been identified as a cellular receptor for EV7. The crystal structure of EV7 has been determined to 3.1-Å resolution and used to interpret the 7.2-Å-resolution cryo-electron microscopy reconstruction of EV7 complexed with DAF. Each DAF binding site on EV7 is near a 2-fold icosahedral symmetry axis, which differs from the binding site of DAF on the surface of coxsackievirus B3, indicating that there are independent evolutionary processes by which DAF was selected as a picornavirus accessory receptor. This suggests that there is an advantage for these viruses to recognize DAF during the initial process of infection.

AB - Echovirus 7 (EV7) belongs to the Enterovirus genus within the family Picornaviridae. Many picornaviruses use IgG-like receptors that bind in the viral canyon and are required to initiate viral uncoating during infection. However, in addition, some of the enteroviruses use an alternative or additional receptor that binds outside the canyon. Decay-accelerating factor (DAF) has been identified as a cellular receptor for EV7. The crystal structure of EV7 has been determined to 3.1-Å resolution and used to interpret the 7.2-Å-resolution cryo-electron microscopy reconstruction of EV7 complexed with DAF. Each DAF binding site on EV7 is near a 2-fold icosahedral symmetry axis, which differs from the binding site of DAF on the surface of coxsackievirus B3, indicating that there are independent evolutionary processes by which DAF was selected as a picornavirus accessory receptor. This suggests that there is an advantage for these viruses to recognize DAF during the initial process of infection.

UR - http://www.scopus.com/inward/record.url?scp=78649414884&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78649414884&partnerID=8YFLogxK

U2 - 10.1128/JVI.00837-10

DO - 10.1128/JVI.00837-10

M3 - Article

C2 - 20881044

AN - SCOPUS:78649414884

VL - 84

SP - 12665

EP - 12674

JO - Journal of Virology

JF - Journal of Virology

SN - 0022-538X

IS - 24

ER -

Plevka P, Hafenstein S, Harris KG, Cifuente JO, Zhang Y, Bowman VD et al. Interaction of decay-accelerating factor with echovirus 7. Journal of virology. 2010 Dec 1;84(24):12665-12674. https://doi.org/10.1128/JVI.00837-10